Alkalosis Health Dictionary

The balance between the acid and alkaline elements present in the blood and body ?uids.

The normal hydrogen ion concentration of the PLASMA is a constant pH 7·4, and the lungs and kidneys have a crucial function in maintaining this ?gure. Changes in pH value will cause ACIDOSIS or ALKALOSIS.... acid base balance

Royle.

Family: Gentianaceae.

Habitat: Kashmir and North-West Himalayas.

English: Himalayan Gentian, Indian Gentian Root.

Ayurvedic: Traayamaana, Traayanti, Traayanta, Traayantikaa, Neelkan- thi, Anujaa, Girijaa, Girishaanujaa, Balbhra, Paalani. (Paakhaanabheda is a wrong synonym)

Unani: Ghaafis.

Action: Sialagogue, digestant, appetite-stimulant, antispasmodic, anti-inflammatory, emmenagogue. Used for alkalosis, feeble digestion in the elderly from gastric acid deficiency (increases gastric juices without altering PH); also used for jaundice, nausea, vomiting, travel sickness, diarrhoea, malaria and nervous exhaustion. (In Chinese medicine, Gentiana sp., known as Longdan, are used for jaundice, hepatitis, urinary tract infections, pruritis and eczema.)

Key application: Gentiana lutea— internally, for digestive disorders, such as lack of appetite, fullness and flatulence (German Commission E, WHO), for anorexia following illness and dyspepsia (ESCOP). The British Herbal Compendium approves gentian for lack of appetite, anorexia, atonic dyspepsia, gastrointestinal atony, and as antiemetic. The British Herbal Pharmacopoia recognizes it as a bitter tonic.

The rhizome and roots of G. Kur- roo contain iridoid glycoside; major component was identified as 6'- cinnamoylcatalpol.

The rhizomes and roots of Picro- rhiza kurrooa Royle ex Benth., found in the Himalayas, have similar properties and uses and are mixed or substituted for those of G. kurroo.

Gentiana lutea (Yellow Gentian) is a native of Europe and Asia Minor and is imported into India. The most important constituents of the drug are secoiridoid bitter compounds, amaro- gentin and gentiopicroside, together with traces of swertiamarin and sweroside. The roots also contain alkaloids, gentianine and gentioflavine, xanthones, and bitter oligosaccharides, gentiobiose and gentianose.

Amarogentin, gentiopicrin, swer- tiamarin, sioeroside (iridoid monoter- penes) are toxic constituents.

Gentiana tenella Rottb., synonym Gentianella tenella H. Smith and G. decumbens Linn.f. occur at high altitudes in the Himalayas, and are used as substitutes for gentian. G. tenella is known as Kadu in Kashmir and Titaa in Punjab. The rhizome is used as Traayamaana in Ayurvedic medicine.

The flowering tops of G. olivieri Griseb., synonym G. dahurica Fisch., used in Unani medicine as Gul-e- Ghaafis, are imported into India from Persia.

Dosage: Root—1-3 g powder. (CCRAS.)... gentiana kurroo

Narrowing of the PYLORUS, the muscular exit from the STOMACH. It is usually the result of a pyloric ulcer or cancer near the exit of the stomach. Food is delayed when passing from the stomach to the duodenum and vomiting occurs. The stomach may become distended and peristalsis (muscular movement) may be seen through the abdominal wall. Unless surgically treated the patient will steadily deteriorate, losing weight, becoming dehydrated and developing ALKALOSIS.

A related condition, congenital hypertrophic pyloric stenosis, occurs in babies (commonly boys) about 3–5 weeks old, and surgery produces a complete cure.... pyloric stenosis

Gentiana lutea L. German: Gelberenzian. French: Gentiane jaune. Italian: Genziana gialla. Arabian: Jintiyania. Indian: Pakhanbhed. Iranian: Gintiyana. Dried rhizomes and roots.

Constituents: Xanthones, iridoids, alkaloids, phenolic acids, pectin, gum, no tannin.

Action: well-known traditional European bitter (all bitters are liver and pancreatic stimulants). Haemopoietic action speeds production of red blood cells. (Should not be given for overproduction of red blood cells as in polycythaemia.) Emmenagogue, sialagogue, antispasmodic, anti-inflammatory, anthelmintic. King of tonics. Digestant, increases gastric juices by 25 per cent, without altering pH. Appetite stimulant.

Uses: Alkalosis, feeble digestion in the elderly from gastric acid deficiency. Thin people anxious to put on weight. Jaundice – promotes flow of bile. Nausea, vomiting, travel sickness (with or without Ginger), bitter taste in mouth, diarrhoea with yellow stool, malaria (as a substitute for Quinine), post-influenzal or ME depression and lack of appetite, severe physical exhaustion (Ginseng). To antidote some types food- poisoning (salmonella, shigella, etc).

Preparations: Thrice daily. Average dose half-2g. Before meals.

Decoction: half-1 teaspoon to cup cold water; steep overnight. Dose: half a cup.

Tincture: 1 part powdered root to 5 parts Vodka; macerate 8 days. Dose: 1-2 teaspoons.

Tablets: formula. Skullcap 45mg; Hops 45mg; Asafoetida 30mg, and the aqueous extractive from 120mg Gentian and 90mg Valerian. Two tablets thrice daily for nervous exhaustion and stress disorders. Anorexia nervosa, specific combination: equal parts – Gentian and Valerian roots. One heaped teaspoon to each cup cold water; steep overnight. Dose – half a cup the following day, morning and evening. Contra-indications: pregnancy, hyperacidity. Gastric ulcer.

Note: An ingredient of anti-smoking preparations. Well-known in Chinese medicine. ... gentian

A combination of mechanisms that ensures that the body’s fluids are neither too acid nor too alkaline (alkalis are also called bases).

The body has three mechanisms for maintaining normal acid–base balance: buffers, breathing, and the activities of the kidneys. Buffers are substances in the blood that neutralize acid or alkaline wastes. Rapid breathing results in the blood becoming less acidic; slow breathing has the opposite effect. The kidneys regulate the amounts of acid or alkaline wastes in the urine.

Disturbances of the body’s acid–base balance result in either acidosis (excessive blood acidity) or alkalosis (excessive blood alkalinity).... acid–base balance

A rare type of hypercalcaemia accompanied by alkalosis and kidney failure. The syndrome is due to excessive, long-term intake of calciumcontaining antacid drugs and milk. It is most common in people with a peptic ulcer and associated kidney disorders. Symptoms include weakness, muscle pains, irritability, and apathy. Treatment is to reduce milk and antacid intake.... milk–alkali syndrome

the balance between the amount of carbonic acid and bicarbonate in the blood, which must be maintained at a constant ratio of 1:20 in order to keep the hydrogen ion concentration of the plasma at a constant value (pH 7.4). Any alteration in this ratio will disturb the acid-base balance of the blood and tissues and cause either *acidosis or *alkalosis. The lungs and the kidneys play an important role in the regulation of the acid-base balance.... acid-base balance

n. abnormally high blood alkalinity. This may be caused by an increase in the concentration of alkaline substances and/or a decrease in that of acidic substances in the blood. See also alkalosis. Compare acidaemia.... alkalaemia

(mountain sickness) the condition that results from unaccustomed exposure to a high altitude (4500 m or more above sea level). Reduced atmospheric pressure and shortage of oxygen cause deep rapid breathing (*hyperventilation), which lowers the concentration of carbon dioxide in the blood (see alkalosis). Symptoms include nausea, exhaustion, and anxiety. In severe cases there may be acute shortness of breath due to fluid collecting in the lungs (pulmonary *oedema), which requires treatment by diuretics and return to a lower altitude.... altitude sickness

a rare autosomal *dominant condition characterized by hypertension associated with hypokalaemia, metabolic alkalosis, and low levels of plasma *renin and *aldosterone. The hypertension often starts in infancy and is due to excess resorption of sodium and excretion of potassium by the renal tubules. The syndrome is caused by a single genetic mutation on chromosome 16, which results in dysregulation of a sodium channel in the distal convoluted tubule. Treatment is with a low salt diet and a potassium-sparing diuretic that directly blocks the sodium channel, such as amiloride or triamterene. [G. G. Liddle (1921–89), US endocrinologist]... liddle’s syndrome

n. spasm and twitching of the muscles, particularly those of the face, hands, and feet. Tetany is usually caused by a reduction in the blood calcium level, which may be due to underactive parathyroid glands, rickets, or *alkalosis.... tetany