Aza Health Dictionary

A CYTOTOXIC and an immunosuppressive drug (see IMMUNOSUPPRESSION). In the ?rst of these capacities it is proving to be of value in the treatment of acute leukaemia. As an immunosuppressive agent it reduces the antibody response of the body (see ANTIBODIES), and is thereby helping to facilitate the success of transplant operations (see TRANSPLANTATION) by reducing the chances of the transplanted organ (e.g. the kidney) being rejected by the body. Azathioprine is also proving to be of value in the treatment of AUTOIMMUNE DISORDERS.... azathioprine

See visceral leishmaniasis.... kala azar

(Persian) Of the dry earth; free of material things... azadeh

A. Juss.

Synonym: Melia azadirachta Linn.

Family: Meliaceae.

Habitat: Native to Burma; found all over India.

English: Neem tree, Margosa tree.

Ayurvedic: Nimba, Nimbaka, Arishta, Arishtaphala, Pichumarda, Pichumanda, Pichumandaka, Tiktaka, Sutiktak, Paaribhadra.

Unani: Aazaad-Darakht-e-Hindi.

Siddha/Tamil: Vemmu, Veppu, Veppan, Arulundi.

Action: Leaf, bark—antimicrobial, antifungal, anthelmintic, insecti- cidal, antiviral, antipyretic, anti- malarial, antiperiodic, mosquito larvicidal, anti-inflammatory, antifertility, spermicidal, hypogly- caemic; used in inflammation of gums, gingivitis, periodonitis, sores, boils, enlargement of spleen, malarial fever, fever during childbirth, measles, smallpox, head scald and cutaneous affections. Oil—used as a contraceptive for intravaginal use, for the treatment of vaginal infections, and as a mosquito repellent.

Plant tetranortriterpenoids have been examined extensively for their antibiotic, antitumour, insecticidal, antibacterial and antifungal activities.

The methanolic extract of the bark shows antimalarial activity against Plasmodium falciparum.

The aqueous extract of leaves exhibited antiulcer and anti-inflammatory activity.

The water-soluble portion of alcoholic extract of leaves reduces blood sugar in glucose-fed and adrenaline- induced hyperglycaemic rats (but not in normal and streptozotocin-induced diabetic rats).

A volatile fraction of the Neem oil is reported to be responsible for sper- micidal activity at a dose of 25 mg/ml for human sperm. The oil has been found to retard the growth of human immunodeficiency virus.

Neem oil has caused mitochondri- al injury in mice; poisonous in high doses. (Sharon M. Herr.)

Dosage: Dried leaf—1-3 g powder; 10-20 g for decoction; stembark— 2-4 g powder decoction for external use. (API Vol. II.) Leaf juice— 10-20 ml; oil—5-10 drops; bark decoction—50-100 ml. (CCRAS.)... azadirachta indica

(Latin / Hebrew) Of the dry earth; resembling the flower / one who is spared by God

Azalia, Azaleah, Azaley, Azalee, Azaleigh, Azalie, Azalei, Azali, Azaly, Azelia, Azalya, Azelya, Azelea, Azelie, Aziel, Azhar, Azhara... azalea

(African) One who is superior Azanah, Azanna, Azannah... azana

(Hebrew) One who is heard by God Azaniah, Azanea, Azaneah, Azaniya, Azaniyah... azania

(Persian) One who is fiery; scarlet Azara, Azaria, Azarah, Azarra, Azarrah, Azarr... azar

A protozoan disease caused by Leishmania donovani, found around parts of the Mediterranean basin, tropical Africa, South America, and central and eastern Asia. The disease is transmitted byfemale sandflies of the genus, Phlebotomus in the Old World and Lutzomyia in the New World. Full-blown disease is often fatal, if untreated. Growth nodules of the disease or leishmanioma form initially and, if spontaneous recoverydoes not occur, proliferating parasites burst out of the nodules, disseminating throughout the body.... visceral leishmaniasis (kala azar)