Centratherum anthelminticum Health Dictionary

Centratherum Anthelminticum: From 1 Different Sources


Kuntze.

Synonym: Vernonia anthelmintica Willd.

Family: Asteraceae.

Habitat: Throughout India up to 2,000 m in the Himalayas and Khasi Hills.

English: Purple Flea-bane, Achenes.

Ayurvedic: Aranya-Jiraka, Vanajira- ka, Kaalijiri, Karjiri. Somaraaji (also equated with Psoralea corylifolia Linn., Papilionaceae).

Unani: Kamoon barri.

Siddha/Tamil: Kaattu seerakam.

Action: Anthelmintic (against earthworms and tapeworms), stomachic, diuretic; used in skin diseases.

Delta-7-avenasterol is the main active principle of seeds. Seed oil contains vernasterol. Seeds bitter principle is a demanolide lactone. Centratherin and germacranolide from the leaves and stem have been isolated. Leaves contain abscisic acid. EtOH extract of achenes exhibited good results in giar- diasis. Various plant parts are used in syphilis. Clinical studies on vircarcika eczema validated the use of the drug in skin diseases.

The drug exhibited smooth muscle- relaxant and hypotensive activity in animals.

Dosage: Seed—1-3 g powder. (CCRAS.)

Dosage: Seed—1-3 g powder. (CCRAS.)
Health Source: Indian Medicinal Plants
Author: Health Dictionary

Psoralea Corylifolia

Linn.

Family: Papilionaceae; Fabaceae.

English: Babchi, Purple Fleabane.

Habitat: Rajasthan., eastern districts of Punjab and adjoining areas of Uttar Pradesh.

Ayurvedic: Somaraaji, Somavalli, Somavallik, Soma, Chaandri, Vaakuchi, Baakuchi, Avalguja. (Somaraaji and Avalguja have also been equated with Centratherum anthelminticum.)

Unani: Baabchi, Bakuchi.

Siddha/Tamil: Karpoogaarisi.

Action: Seed—used in leucoderma, vitiligo, leprosy, psoriasis and inflammatory diseases of the skin, both orally and externally. (The Ayurvedic Pharmacopoeia of India.)

The seed and roots contain chal- cones, flavones, isoflavones, furano- coumarins and coumesterol group of compounds. These include psoralen, isopsoralen, bavachinin.

A mixture of psoralen and isopso- ralen, in a ratio of 1:3, is recommended for topical application in leucoderma. These furanocoumarins initiate transformation of DOPA to melanin under the influence of UV light. Seeds are powdered and administered orally with warm water (5 g/day) in cases of eczema.

Psoralen was found to be cytotoxic in vitro. The combination therapy of psoralen and UV irradiation has been shown to inhibit the growth of tumours in vivo.

Bavachinin-A, isolated from the fruits, exhibited marked anti-inflammatory, antipyretic and mild analgesic properties similar to those of oxyphenylbutazone and hydrocortisone. It demonstrated better antipyretic activity than paracetamol experimentally.

Oral administration of the powdered seeds has generally resulted in side reactions (nausea, vomiting, purging); external application generally proved highly irritant to the skin.

Dosage: Seed—1-3 g powder (CCRAS.); 3-6 g powder (API, Vol. I).... psoralea corylifolia

Wormseed

Chenopodium ambrosioides var. anthelminticum

FAMILY: Chenopodiaceae

SYNONYMS: C. anthelminticum, American wormseed, chenopodium, Californian spearmint, Jesuit’s tea, Mexican tea, herb sancti mariae, Baltimore (oil).

GENERAL DESCRIPTION: A hairy, coarse, perennial wayside herb up to 1 metre high with stout, erect stem, oblong-lanceolate leaves and numerous greenish-yellow flowers, the same colour as the leaves.

DISTRIBUTION: Native to South America; cultivated mainly in the east and south east USA, also India, Hungary and the USSR.

OTHER SPECIES: The parent plant, C. ambrosioides, is also used to produce an essential oil with similar properties. There are many different members in the Chenopodium or Goosefoot family, such as Good King Henry (C. bonus-henricus), a European variety whose leaves were eaten like spinach. See also Botanical Classification section.

The so-called ‘Russian wormseed oil’ or wormseed Levant (Artemisia cina) is quite different from the American type, although it is also used as an anthelmintic and is extremely toxic, containing mainly cineol.

HERBAL/FOLK TRADITION: ‘Used for many years by the local Indians as an effective anthelmintic ... several Indian tribes of the eastern part of the United States use the whole of the herb decocted to help ease painful menstruation and other female complaints.’. Apart from being used to expel roundworm, hookworm and dwarf tapeworm, the herb has also been employed for asthma, catarrh and other chest complaints, and to treat nervous disease. In China it is used to treat articular rheumatism. Causes dizziness and vomiting in concentration.

ACTIONS: Anthelmintic, antirheumatic, antispasmodic, expectorant, hypotensive.

EXTRACTION: Essential oil by steam distillation from the whole herb, especially the fruit or seeds.

CHARACTERISTICS: A colourless or pale yellow oil with a sweet-woody, camphoraceous, heavy and nauseating odour.

PRINCIPAL CONSTITUENTS: Ascaridole (60–80 per cent), cymene, limonene, terpinene, myrcene.

SAFETY DATA: A very toxic oil – cases of fatal poisoning have been reported even in low doses. Effects can be cumulative. Due to high ascaridole content, the oil may explode when heated or treated with acids.

AROMATHERAPY/HOME: USE None. ‘Should not be used in therapy either internally or externally. One of the most toxic essential oils.’.

OTHER USES: In pharmaceuticals its anthelmintic applications have been replaced by synthetics. Used as a fragrance component in soaps, detergents, cosmetics and perfumes. Its use is not permitted in foods.... wormseed




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