Creatinine clearance Health Dictionary

It is the waste product of creatine, an enzyme found in large amounts throughout the tissues, and mainly excreted in the urine. The parent compound creatine enables the body to use the “blue flame” of anaerobic combustion (as opposed to the yellow flame of oxidation). Elevated creatinine in the blood may be an early symptom of kidney disease.... creatinine

The volume of blood from which a drug is completely removed in one minute is known as clearance. Renal clearance of a drug is the amount of blood completely cleared of the drug by the kidney in one minute.... drug clearance

(renal clearance) n. a quantitative measure of the rate at which waste products are removed from the blood by the kidneys or through the process of dialysis. It is expressed in terms of the volume of blood that could be completely cleared of a particular substance in a particular unit of time. Clearance by the kidney is usually measured as ml/min while clearance with, say, peritoneal dialysis is usually measured in litres/week.... clearance

a laboratory measurement used as a screening test for the first signs of kidney damage in *diabetes mellitus. It detects an increase in the very small levels of the protein albumin present in urine, relative to the concentration of creatinine. It is best measured in an early morning urine sample. See microalbuminuria.... microalbumin:creatinine ratio