Lung Volumes: From 1 Different Sources
The volume of air within the LUNGS changes with the respiratory cycle (see RESPIRATION). The volumes de?ned in the following table can be measured, and may be useful indicators of some pulmonary diseases.
Normal values for a 60 kg man are (in ml):
Total lung capacity (TLC) The volume of air that can be held in the lungs at maximum inspiration.
Tidal volume (TV) The volume of air taken into and expelled from the lungs with each breath.
Inspiratory reserve volume (IRV) The volume of air that can still be inspired at the end of a normal quiet inspiration.
Expiratory reserve volume (ERV) The volume of air that can still be expired at the end of a normal quiet expiration.
Residual volume (RV) The volume of air remaining in the lungs after a maximal expiration.
Vital capacity (VC) The maximum amount of air that can be expired after a maximal inspiration.
Functional residual capacity (FRC) The volume of air left in the lungs at the end of a normal quiet expiration.
Allergic alveolitis. An occupational lung disease due to inhaling dust and mouldy grain, hay or other mouldy vegetable produce. Usually affects farm workers and those exposed to its wide range of allergens.
Symptoms: Influenza-like fever, breathlessness, cough.
Prognosis: Chronic lung damage and progressive disability.
Indicated: antifungals, antibiotics.
Alternatives. Teas. Marigold, Ground Ivy, Scarlet Pimpernel, Yarrow. 1 heaped teaspoon to each cup boiling water; infuse 5-15 minutes; 1 cup freely.
Tablets/capsules. Garlic, Echinacea, Goldenseal, Thuja.
Powders. Combine, parts, Echinacea 3; Goldenseal 1; Thuja 1. Dose: 500mg, (two 00 capsules or one- third teaspoon) thrice daily.
Decoction. Irish Moss, to promote expectoration and eliminate debris.
Tinctures. Alternatives. (1) Echinacea 2; Lobelia 1; Liquorice 1. (2) Equal parts: Wild Indigo, Thuja and Pleurisy root. (3) Echinacea 2; Marigold 1; Thuja half; Liquorice half. Dosage: two 5ml teaspoons in water thrice daily. Acute cases: every 2 hours.
Topical. Inhalation of Eucalyptus or Tea Tree oils.
Diet. See: DIET – GENERAL. Yoghurt in place of milk.
Note: Bronchodilators of little value. Those at risk should have an X-ray at regular intervals. ... farmer’s lung
A device that temporarily takes over the function of the heart and lungs. It is used in certain operations in the chest, giving the surgeon more time for operations such as open-heart surgery, heart transplants and heart-lung transplants. The machine also ensures an operating area largely free of blood, which helps the surgeon to work more quickly. A pump replaces the heart and an oxygenator replaces the lungs. When connected up, the machine in e?ect bypasses normal cardiopulmonary activity. It also contains a heat exchanger to warm or cool the patient’s blood according to the requirements of the operation. The patient is given an anticoagulant (HEPARIN) to counteract clotting which may occur when blood cells get damaged during the machine’s use. Patients are on the machine for a few hours only, because blood supply to vital organs begins to be reduced.... heart-lung machine
A large machine formerly used to maintain breathing, especially in people paralysed by poliomyelitis. The iron lung has been replaced by more efficient means of maintaining breathing (see ventilation).... iron lung
Also known as pigeon breeder’s lung, this is a form of extrinsic allergic ALVEOLITIS resulting from sensitisation to birds. In bird fanciers, skin tests sometimes show sensitisation to birds’ droppings, eggs, protein and serum, even through there has been no evidence of any illness.... bird fancier’s lung
Budgerigar-fancier’s lung is a form of extrinsic allergic ALVEOLITIS, resulting from sensitisation to budgerigars, or parakeets as they are known in North America. Skin tests have revealed sensitisation to the birds’ droppings and/or serum. As it is estimated that budgerigars are kept in 5– 6 million homes in Britain, current ?gures suggest that anything up to 900 per 100,000 of the population are exposed to the risk of developing this condition.... budgerigar-fancier’s lung
A form of external allergic ALVEOLITIS caused by the inhalation of dust from mouldy hay or straw.... farmer’s lung
An operation in which a patient’s diseased lungs and heart are removed and replaced with donor organs from someone who has been certi?ed as ‘brain dead’ (see BRAIN-STEM DEATH). As well as the technical diffculties of such an operation, rejection by the recipient’s tissues of donated heart and lungs has proved hard to overcome. Since the early 1990s, however, immunosuppressant drug therapy (see CICLOSPORIN; TRANSPLANTATION) has facilitated the regular use of this type of surgery. Even so, patients receiving transplanted hearts and lungs face substantial risks such as lung infection and airway obstruction as well as the long-term problems of transplant rejection.... heart-lung transplant
Trematode worms infecting the lungs of humans and other crab-eating mammals. Belong to the genusParagonimus and are found in parts of Africa, Latin America, Asia and SE Asia.... lung flukes
See ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS).... shock lung
An operation to cut out one of the lobes of a lung, usually to remove a cancerous tumour.... lobectomy, lung
See pulmonary disease, chronic obstructive.... lung disease, chronic obstructive
See pulmonary function tests.... lung function tests
A machine that temporarily takes over the function of the heart and lungs to facilitate operations such as open heart surgery, heart transplants, and heart–lung transplants.
A heart–lung machine consists of a pump (to replace the heart’s function) and an oxygenator (to replace the lung’s function). It bypasses the heart and lungs, and the heart can be stopped.
Use of a heart–lung machine tends to damage red blood cells and to cause blood clotting. These problems can be minimized, however, by the administration of heparin, an anticoagulant drug, beforehand.heart–lung transplant A procedure in which the heart and lungs of a patient are removed, and replaced with donor organs. This surgery is used to treat diseases in which the lung damage has affected the heart, or vice versa. Such diseases include cystic fibrosis, fibrosing alveolitis, and some severe congenital heart defects (see heart disease, congenital). A heart–lung machine is used to take over the function of the patient’s heart and lungs during the operation, which is no more dangerous than a heart transplant.
heart-rate The rate at which the heart contracts to pump blood around the body. Most people have a heart-rate of between 60 and 100 beats per minute at rest. This rate tends to be faster in childhood and to slow slightly with age. Very fit people may have a resting rate below 60 beats per minute.
The heart muscle responds automatically to any increase in the amount of blood returned to it from active muscles by increasing its output. During extreme exercise, heart-rate may increase to 200 contractions per minute and the output to almost 250 ml per beat.
The heart-rate is also regulated by the autonomic nervous system. The parts of this system concerned with heart action are a nucleus of nerve cells, called the cardiac centre, in the brainstem, and 2 sets of nerves (the parasympathetic and sympathetic).
At rest, the parasympathetic nerves – particularly the vagus nerve – act on the sinoatrial node to maintain a slow heart-rate. During or in anticipation of muscular activity, this inhibition lessens and the heart-rate speeds up.
Sympathetic nerves release noradrenaline, which further increases the heart-rate and force of contraction. Sympathetic activity can be triggered by fear or anger, low blood pressure, or a reduction of oxygen in the blood.
Release of adrenaline and noradrenaline by the adrenal glands also acts to increase heart-rate.
The rate and rhythm of the heart can be measured by feeling the pulse or by listening with a stethoscope; a more accurate record is provided by an ECG.
A resting heart-rate above 100 beats per minute is termed a tachycardia, and a rate below 60 beats per minute a bradycardia. (See also arrhythmia, cardiac.)... heart–lung machine
a form of extrinsic allergic *alveolitis caused by the inhalation of avian proteins present in the droppings and feathers of certain birds, especially pigeons and caged birds (such as budgerigars). As in *farmer’s lung, there is an acute and a chronic form.... bird-fancier’s lung
the honeycomb pattern seen on X-ray at the later stages of chronic lung conditions, in which the lungs become less elastic and more fibrotic. Once the honeycomb appearance is visible on the X-ray, the lungs are likely to progress to respiratory failure.... honeycomb lung
cancer arising in the epithelium of the air passages (bronchial cancer) or lung (see also non-small-cell lung cancer; small-cell lung cancer). It is a very common form of cancer, particularly in Britain, and is strongly associated with cigarette smoking and exposure to industrial air pollutants (including asbestos). There are often no symptoms in the early stages of the disease, when diagnosis is made on X-ray examination. Treatment includes surgical removal of the affected lobe or lung (less than 20% of cases are suitable for surgery), radiotherapy, and chemotherapy.... lung cancer
a form of extrinsic allergic *alveolitis seen in people who work with barley.... malt-worker’s lung
(NSCLC) any type of lung cancer other than *small-cell lung cancer. Such cancers include *adenocarcinoma of the lung, large-cell carcinomas, and squamous-cell carcinoma of the lung.... non-small-cell lung cancer
(SCLC) a type of bronchial carcinoma characterized by small cells (or oat cells), small round or oval cells with darkly staining nuclei and scanty indistinct cytoplasm. Small-cell carcinoma is usually related to smoking and accounts for about one-quarter of bronchial carcinomas; it carries a poor prognosis due to early distant spread, typically to bones, liver, and brain. Treatment is primarily with chemotherapy and radiotherapy and paraneoplastic symptoms (see paraneoplastic syndrome) from *ectopic hormone production are common. Compare non-small-cell lung cancer.... small-cell lung cancer
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