Methanol poisoning usually occurs as a result of drinking it as a substitute for ordinary alcohol.
Symptoms of poisoning include headache, dizziness, nausea, vomiting, and unconsciousness.
Damage may also occur to the retina and the optic nerve, causing blurred vision.
Repeated or large doses of methanol may result in permanent blindness.
Ben: Kalmegh
Mal: Nilaveppu, Kiriyattu Tam: Nilavempu Kan: KreataImportance: Kalmegh, the Great or Green Chiretta is a branched annual herb. It is useful in hyperdipsia, burning sensation, wounds, ulcers, chronic fever, malarial and intermittent fevers, inflammations, cough, bronchitis, skin diseases, leprosy, pruritis, intestinal worms, dyspepsia, flatulence, colic, diarrhoea, dysentery, haemorrhoids and vitiated conditions of pitta (Warrier et al, 1993). It is used to overcome sannipata type of fever, difficulty in breathing, hemopathy due to the morbidity of kapha and pitta, burning sensation, cough, oedema, thirst, skin diseases, fever, ulcer and worms. It is also useful in acidity and liver complaints (Aiyer and Kolammal, 1962). The important preparations using the drug are Tiktakagheta, Gorocandi gulika, Candanasava, Panchatiktam kasaya, etc. (Sivarajan et al, 1994). A preparation called “Alui” is prepared by mixing powdered cumin (Cuminium cyminum) and large cardamom (Amomum subulatum) in the juice of this plant and administered for the treatment of malaria (Thakur et al, 1989). It is also a rich source of minerals.Distribution: The plant is distributed throughout the tropics. It is found in the plains of India from U.P to Assam, M.P., A.P, Tamil Nadu and Kerala, also cultivated in gardens.Botany: Andrographis paniculata (Burm.f.) Wall ex.Nees belongs to the family Acanthaceae. It is an erect branched annual herb, 0.3-0.9m in height with quadrangular branches. Leaves are simple, lanceolate, acute at both ends, glabrous, with 4-6 pairs of main nerves. Flowers are small, pale but blotched and spotted with brown and purple distant in lax spreading axillary and terminal racemes or panicles. Calyx-lobes are glandular pubescent with anthers bearded at the base. Fruits are linear capsules and acute at both ends. Seeds are numerous, yellowish brown and sub-quadrate (Warrier et al,1993).Another species of Andrographis is A. echioides (Linn.) Nees. It is found in the warmer parts of India. The plant is a febrifuge and diuretic. It contains flavone-echiodinin and its glucoside-echioidin (Husain et al, 1992).Agrotechnology: The best season of planting Andrographis is May-June. The field is to be ploughed well, mixed with compost or dried cowdung and seedbeds of length 3m, breadth 1/2m and 15cm height are to be taken at a distance of 3m. The plant is seed propagated. Seeds are to be soaked in water for 6 hours before sowing. Sowing is to be done at a spacing of 20cm. Seeds may germinate within 15-20 days. Two weedings, first at one month after planting and the second at 2 month after planting are to be carried out. Irrigation during summer months is beneficial. The plant is not attacked by any serious pests or diseases. Flowering commences from third month onwards. At this stage, plant are to be collected, tied into small bundles and sun-dried for 4-5 days. Whole plant is the economic part and the yield is about 1.25t dried plants/ha (Prasad et al, 1997).Properties and activity: Leaves contain two bitter substances lactone “andrographolid” and “kalmeghin”. The ash contains sodium chloride and potassium salts. Plant is very rich in chlorophyte. Kalmeghin is the active principle that contains 0.6% alkaloid of the crude plant. The plant contains diterpenoids, andrographolide, 14-deoxy-11-oxo-andrographolide, 14-deoxy-11,12-dihydroandrographolide, 14-deoxy andrographolide and neoandrographolide (Allison et al, 1968). The roots give flavones-apigenin-7,4-dio-O-methyl ether, 5-hydroxy-7,8,2’,3’- tetramethoxyflavone, andrographin and panicolin and -sitosterol (Ali et al, 1972; Govindachari et al, 1969). Leaves contain homoandrographolide, andrographosterol and andrographone.The plant is vulnerary, antipyretic, antiperiodic, anti-inflammatory, expectorant, depurative, sudorific, anthelmintic, digestive, stomachic, tonic, febrifuge and cholagogue. The plant is antifungal, antityphoid, hepatoprotective, antidiabetic and cholinergic. Shoot is antibacterial and leaf is hypotensive(Garcia et al, 1980). This is used for the inflammation of the respiratory tract. In China, researchers have isolated the andrographolide from which soluble derivative such as 14-deoxy-11, 12-dehydro-andrographolide which forms the subject of current pharmacological and clinical studies. Apigenin 7,4’-O-dimethyl ether isolated from A. paniculata exhibits dose dependent, antiulcer activity in shay rat, histamine induced ulcer in guinea pigs and aspirin induced ulcers in rats. A crude substance isolated from methanolic extract of leaves has shown hypotensive activity. Pre-treatment of rats with leaf (500mg/kg) or andrographolide (5mg/kg) orally prevented the carbon tetrachloride induced increase of blood serum levels of glutamate-oxaloacetate transaminase in liver and prevented hepatocellular membrane.... green chirettaAlcohol is a drug and produces a wide range of mental and physical effects. The effect of alcohol on the central nervous system is as a depressant, decreasing its activity and thereby reducing anxiety, tension, and inhibitions. In moderate amounts, alcohol produces a feeling of relaxation, confidence, and sociability. However, alcohol slows reactions, and the more that is drunk, the greater is the impairment of concentration and judgement. Excessive consumption of alcohol results in poisoning or acute alcohol intoxication, with effects ranging from euphoria to unconsciousness.
Short-term physical effects of alcohol include peripheral vasodilation (widening of the small blood vessels), which causes the face to flush, and increased flow of gastric juices, which stimulates the appetite. Alcohol increases sexual confidence, but high levels can cause impotence. Alcohol also acts as a diuretic, increasing urine output.
In the long term, regular excessive alcohol consumption can cause gastritis (inflammation and ulceration of the stomach lining), and lead to alcoholrelated disorders.
Heavy drinking in the long term may also lead to alcohol dependence.
However, people who drink regular, small amounts of alcohol (an average of 1–2 units a day) seem to have lower rates of coronary heart disease and stroke than total abstainers.... alcohol
Habitat: Throughout the country, ascending to an altitude of about 1,050 m in the outer Himalayas.
English: Indian Wild Liquorice, Jequirity, Crab's Eye, Precatory Bean.Ayurvedic: Gunjaa, Gunjaka, Chirihintikaa, Raktikaa, Chirmi- ti, Kakanti, Kabjaka, Tiktikaa, Kaakananti, Kaakchinchi. (Not to be used as a substitute for liquorice.)Unani: Ghunghchi, Ghamchi.Siddha/Tamil: Kunri.Folk: Chirmiti, Ratti.Action: Uterine stimulant, abortifa- cient, toxic. Seeds—teratogenic. A paste of seeds is applied on vitiligo patches.
Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India has indicated the use of seeds in baldness.Seeds contain abrin, a toxalbumin, indole derivatives, anthocyanins, ste- rols, terpenes. Abrin causes agglutination of erythrocytes, haemolysis and enlargement of lymph glands. A non- toxic dose of abrin (1.25 mcg/kg body weight), isolated from the seeds of red var., exhibited a noticeable increase in antibody-forming cells, bone marrow cellularity and alpha-esterase-positive bone marrow cells.Oral administration of agglutinins, isolated from the seeds, is useful in the treatment of hepatitis and AIDS.The seed extract exhibited antischis- tosomal activity in male hamsters.The methanolic extract of seeds inhibited the motility of human spermatozoa.The roots contain precol, abrol, gly- cyrrhizin (1.5%) and alkaloids—abra- sine and precasine. The roots also contain triterpenoids—abruslactone A, methyl abrusgenate and abrusgenic acid.Alkaloids/bases present in the roots are also present in leaves and stems.A. fruticulosus Wall. Ex Wight and Arn. synonym A. pulchellus Wall., A. laevigatus E. May. (Shveta Gunjaa) is also used for the same medicinal purposes as A. precatorius.Dosage: Detoxified seed—1-3 g powder. Root powder—3-6 g. (API Vols. I, II.)... abrus precatoriusHabitat: Native to China; cultivated in northern India.
English: Lesser Galangal, Alpinia, Catarrh Root, Chinese Ginger.Ayurvedic: Kulanjan (var.). Unani: Khulanjaan (smaller var.). Siddha/Tamil: Chitrarattai.Action: Rhizome—a circulatory stimulant and carminative.
Key application: As a carminative.(The British Herbal Pharmacopoeia.)Aqueous and methanolic extracts of the rhizome, on oral administration, exhibited significant decrease in gastric secretion in rabbits and showed anticholinergic effect in pylorus-ligated rats.Flavones from rhizomes are strongly antifungal against a wide variety of pathogenic fungi, responsible for major skin diseases in eastern India. Flavones were also found to be active against a number of Gram-positive and Gram-negative bacteria.The gingerols and diaryheptanoids constituents of the rhizome are potent inhibitors of PG synthetase (prosta- glandin biosynthesizing enzyme); they can also be active against 5-lipoxyge- nase, an enzyme involved in leuko- triene biosynthesis. (Natural Medicines Comprehensive Database, 2007.)... alpinia officinarumHabitat: Northwestern Himalayas from Kashmir eastwards to Nepal, hills of West Bengal; Central and southern India.
English: Bird's Eye, Bird's Tongue, Blue Pimpernel, Scarlet Pimpernel.Unani: Anaaghaalis.Folk: Jonkmaari (Maharashtra), Dhabbar (Punjab), Jighanaa, Jenghani.Action: Plant—anti-inflammatory, astringent, deobstructant, an- tifungal, nematocidal; toxic to leeches.
The plant yields anagalligenone B. The presence of quaternary alkaloids, gluco-fructoside and tannin have been reported. The root yields glycosidic saponins, including cyclamin. An acetyl saponin, isolated from the plant, was found to possess marked taenici- dal activity but had no effect on round- worms.A methanolic extract of the aerial parts showed activity against herpes simplex I, adenovirus type II and polio type II. Triterepene saponins have oestrogenic activity.... anagallis arvensisHabitat: The western Himalayas and Punjab, from Himachal Pradesh to Kumaon, up to 1,500 m.
Ayurvedic: Mushali, (white var.), Mahaashataavari. The black variety is equated with Taalamuuli, Chlorophytum arundinaceum Baker.Unani: Shaqaaqul-e-Hindi.Action: A substitute for A. officinalis.
The root yields asparagin. Sapoge- nins A and B, isolated from the root, were identified as stigmasterol and sarsasapogenin.Action: Diuretic, laxative, car- diotonic, sedative, galactagogue; used for neuritis and rheumatism, as well as for cystitis and pyelitis.
Key application: In irrigation therapy for inflammatory diseases of the urinary tract and for prevention of kidney stones. (German Commission E.). It is contraindicated in kidney diseases and oedema because of functional heart.The root contains steroidal glyco- sides (asparagosides) and bitter glyco- sides; asparagusic acid and its derivatives; asparagines, arginine and ty- rosine; flavonoids, including rutin, kaempferol and quercetrin; polysac- carides and inulin. Asparagine is a strong diuretic source of folic acid and selenium.A spirostanol glycoside, isolated from the methanolic extract of the fruits, has shown 100% immobilization of human spermatozoa.Dosage: Root—3-5 g powder. (CCRAS.)... asparagus adscendensHabitat: Native to Burma; found all over India.
English: Neem tree, Margosa tree.Ayurvedic: Nimba, Nimbaka, Arishta, Arishtaphala, Pichumarda, Pichumanda, Pichumandaka, Tiktaka, Sutiktak, Paaribhadra.Unani: Aazaad-Darakht-e-Hindi.Siddha/Tamil: Vemmu, Veppu, Veppan, Arulundi.Action: Leaf, bark—antimicrobial, antifungal, anthelmintic, insecti- cidal, antiviral, antipyretic, anti- malarial, antiperiodic, mosquito larvicidal, anti-inflammatory, antifertility, spermicidal, hypogly- caemic; used in inflammation of gums, gingivitis, periodonitis, sores, boils, enlargement of spleen, malarial fever, fever during childbirth, measles, smallpox, head scald and cutaneous affections. Oil—used as a contraceptive for intravaginal use, for the treatment of vaginal infections, and as a mosquito repellent.
Plant tetranortriterpenoids have been examined extensively for their antibiotic, antitumour, insecticidal, antibacterial and antifungal activities.The methanolic extract of the bark shows antimalarial activity against Plasmodium falciparum.The aqueous extract of leaves exhibited antiulcer and anti-inflammatory activity.The water-soluble portion of alcoholic extract of leaves reduces blood sugar in glucose-fed and adrenaline- induced hyperglycaemic rats (but not in normal and streptozotocin-induced diabetic rats).A volatile fraction of the Neem oil is reported to be responsible for sper- micidal activity at a dose of 25 mg/ml for human sperm. The oil has been found to retard the growth of human immunodeficiency virus.Neem oil has caused mitochondri- al injury in mice; poisonous in high doses. (Sharon M. Herr.)Dosage: Dried leaf—1-3 g powder; 10-20 g for decoction; stembark— 2-4 g powder decoction for external use. (API Vol. II.) Leaf juice— 10-20 ml; oil—5-10 drops; bark decoction—50-100 ml. (CCRAS.)... azadirachta indicaHabitat: Throughout India as a weed.
English: Horse-purslane, Hogweed.Ayurvedic: Rakta-punarnavaa, Punarnavaa, Katthilla, Shophaghni, Shothaghni. Varshaabhu (also equated with Trianthema portu- lacastrum Linn., which exhibits anti-inflammatory, antipyretic and analgesic activity).Unani: Itsit, Bishkhaparaa.Siddha/Tamil: Mookkirattai.Folk: Gadaha-purnaa.Action: Diuretic, anti-inflammatory, antiarthritic, spasmolytic, antibacterial (used for inflammatory renal diseases, nephrotic syndrome, in cases of ascites resulting from early cirrhosis of liver and chronic peritonitis, dropsy associated with chronic Bright's diseases, for serum uric acid levels). Root—anticon- vulsant, analgesic, expectorant, CNS depressant, laxative, diuretic, abortifacient.
Key application: As diuretic, hepatoprotective. (Indian Herbal Pharmacopoeia.)B. repanda, synonym B. chinensis Linn., roots exhibited antihepatotox- ic activity against carbon tetrachloride galactosamine-and paracetamol- induced intoxication in rats. Powdered root gave encouraging results in spermatorrhoea and leucorrhoea.The chloroform and methanolic extracts of the roots and aerial parts of B. diffusa also exhibited antihepatotox- ic activity against carbon tetrachloride- induced intoxication in rats.Punarnavaa is official in IP as a diuretic. The diuretic action of the drug is attributed to the presence of xanthone, beta-ecdysone. Flavonoid, arbinofura- noside, present in the drug, was found to lower serum uric acid in experimental animals, as also in humans.Punarnavaa has been reported to increase serum protein level and reduce urinary protein extraction in clinical trials in patients suffering with nephrotic syndrome. The activity is attributed to the presence of rotenoids in various parts of the plant.An antifibrinolytic agent, punar- navoside, has been found to stop IUCD-induced bleeding in monkeys. The drug contains quinolizidine alkaloids.Dosage: Whole plant—20-30 g for decoction (API Vol. I); root—1-3 g powder; 10-20 ml fresh juice. (API Vol. III.)... boerhavia diffusaHabitat: Native to India and Malaysia. Cultivated in Bengal and South India, also grown as a hedge plant.
English: Sappan.Ayurvedic: Pattanga, Patanga, Pattraanga, Raktasaara, Ranjana, Pataranjaka, Suranga, Kuchandana.Unani: Bakam.Siddha/Tamil: Patangam, Anaikun- trumani.Folk: Patang.Action: Wood decoction— emmenagogue, antidiarrhoeal; used in skin diseases.
The heartwood gave an anti-inflammatory principle brazilin; amyrin glu- coside, amino acids and carbohydrates. EtOH (50%) extract of stem exhibited semen coagulant activity Aqueous and chloroform extracts of the wood exhibited inhibitory action on cyclic AMP phosphodiesterase. The methanolic extract of the sappan lignan showed sleep-time-elongation effect in mice. Significant anti-hypercholes- terolaemic activity is attributed to ben- zilic compounds.The oil exhibited antibacterial and antifungal activity.Plant pigments find use in facials which are resistant to light, heat and water and are non-irritating.Dosage: Heartwood—5-10 g (API Vol. IV.)... caesalpinia sappanHabitat: Sub-Himalayan tract up to 2,000 m and South Indian hills.
English: Staff tree, Intellect tree.Ayurvedic: Jyotishmati, Paaraavat- padi. Kangunikaa, Kanguni, Vegaa, Maalkaanguni, Svarnalatikaa, Kaakaandaki, Katuveekaa.Unani: Maalkangani.Siddha/Tamil: Vaaluluvai.Action: Seeds—nervine and brain tonic, diaphoretic, febrifugal, emetic. Seed-oil—used for treating mental depression, hysteria and for improving memory; also used for scabies, eczema, wounds, rheumatic pains, paralysis. A decoction of seeds is given in gout, rheumatism, paralysis and for treating leprosy and other skin diseases. Leaves— antidysenteric, emmenagogue. Root—a paste of root-bark is applied to swollen veins and pneumonic affections.
Key application: As a tranquilizer (Indian Herbal Pharmacopoeia) and brain tonic (The Ayurvedic Pharmacopoeia of India). The Ayurvedic Pharmacopoeia of India indicated the use of ripe seed in leucoderma and vitiligo.The seeds are reported to contain the alkaloids, celastrine and paniculatine, which are the active principles of the drug.In experimental animals, the drug showed lowering of leptazol toxicity, motor activity and amphetamine toxi- city, and raising the capacity for learning process. It showed significant CNS depressant effect and a clear synergism with pentobarbital. The seed extract showed hypolipidaemic effect and prevented atherogenesis in rabbits.The seed oil showed tranquillizing effect and hastened the process of learning in experimental animals. It produced fall in blood pressure in anaesthetized dog, depressed the heart of frog, and was found to be toxic to rats.In addition to the seed, 70% alcoholic extract of the plant showed sedative, anti-inflammatory and antipyretic, anti-ulcerogenic effect in experimental animals.Methanolic extract of flowers showed both analgesic and anti- inflammatory activities experimentally.Dosage: Ripe seed, devoid of capsule wall—1-2 g; oil—5-15 drops. (API Vol. II.)... celastrus paniculatusHabitat: Throughout India in tidal forests, wild all over coastal areas; planted in gardens in Tamil Nadu.
English: Smooth Volkameria.Ayurvedic: Putigandhaa, Kundali, Vanajai.Siddha/Tamil: Peenaari, Sangan- kuppi.Folk: Lanjai.Action: Leaf—febrifuge, alterative. Used as a substitute for Swertia chirayita and quinine in remittent and intermittent fevers. The leaf juice is taken orally to relieve muscular pains and stiffness of legs (in tetanus).
The leaves and stem contain a number of triterpenes, neolignans, diter- penoids, sterols and flavones.The roots are prescribed in venereal diseases. The methanolic extract of the roots contains verbascoside which exhibits analgesic and antimicrobial properties.... clerodendrum inermeHabitat: Throughout India, as a weed upto 2,000 m.
English: Nut Grass.Ayurvedic: Musta, Mustaa, Mus- taka, Abda, Ambuda, Ambhoda, Ambodhara, Bhadra, Bhadraa, Bhadramusta, Bhadramustaa, Bhadramustaka, Ghana, Jalada, Jaldhara, Meghaahvaa, Nirada, Vaarida, Vaarivaaha, Payoda, Balaahaka. Ganda-Duurvaa (var.).Unani: Naagarmothaa, Saad-e-Kufi.Siddha/Tamil: Koraikkizhangu.Folk: Mothaa.Action: Carminative, astringent, anti-inflammatory, antirheumat- ic, hepatoprotective, diuretic, antipyretic, analgesic, hypoten- sive, emmenagogue and nervine tonic.
Used for intestinal problems, indigestion, sprue, diarrhoea, dysentery, vomiting and fever; also as a hypoc- holesterolaemic drug and in obesity.Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicated the use of the rhizome in rheumatism, inflammations, dysuria, puerperal diseases and obesity.The tuber is rich in Cu, Fe, Mg and Ni. Beta-sitosterol, isolated from the tubers, exhibits significant anti- inflammatory activity against carra- geenan- and cotton pellet-induced oedema in rats; the activity is comparable to hydrocortisone and phenylbutazone when administered intraperi- toneally.The alcoholic and aqueous extracts of the tubers possess lipolytic action and reduce obesity by releasing enhanced concentrations of biogenic amines from nerve terminals of the brain which suppress the appetite centre. Presence of eudalne group of ses- quiterpenic compounds of sesquiter- pene alcohol, isocyperol is said to play an important role in lipid metabolism.An alcoholic extract of the plant exhibits liver-protective activity against CCL4-induced liver damage in mice.Methanolic extract of the plant stimulates the production of melanin in cultured melanocytes. (Plant extract is used in preparations used for pigmentation of skin and hair, also in suntan gels.) Aqueous-alcoholic extract of the tuber exhibited hypotensive, diuretic, antipyretic and analgesic activities. These are attributed to a triterpenoid.The essential oil (0.5-0.9%) from the tubers contains mainly sesquiterpenes.C. platystilis Br. is equated with Kaivarta-mustaka.Dosage: Rhizome—3-6 g powder; 20-30 ml decoction. (API Vol. III.)... cyperus rotundusHabitat: Native to China; now cultivated mainly in Saharanpur, Dehradun, Muzaffarnagar, Meerut, Kanpur, Bareilly districts of Uttar Pradesh, Amritsar, Gurdaspur and Hoshiarpur districts of Punjab.
English: Loquat, Japanese Medlar.Ayurvedic: Lottaaka (non-classical).Unani: Lokaat.Siddha: Ilakotta, Nokkotta (Tamil).Action: Leaves—used in China and India for the treatment of diabetes mellitus and skin diseases. Fruit— sedative, antiemetic. Flower— expectorant.
The plant contains lipopolysaccha- rides (LPS), which exhibit antirheu- matic activity. LPS is also found useful for treating diabetes mellitus and lowering high cholesterol level. The ethanolic extract of the leaves showed anti-inflammatory activity on carra- geenan-induced oedema in rats and significant hypoglycaemic effect in normal rabbits like the standard drug tolbutamide. The sesquiterpene gly- coside and polyhydroxylated triterpe- noids showed a marked inhibition of glycosuria in genetically diabetic mice; also reduced blood glucose level in nor- moglycaemic rats. The hypoglycaemic effect is mediated through the release of insulin from pancreatic beta cells.The leaves gave ionone-derived gly- cosides and triterpenes. Maslinic and ursolic acids have also been isolated. Maslinic acid possesses significant anti-inflammatory activity. It also exhibits inhibitory effect on histamine- induced contraction in isolated ileum of guinea pig.Hot aqueous extract of the leaves showed hepatoprotective activity experimentally.The leaves yield an essential oil containing nerolidol (61-74%).The presence of an antifungal compound, eriobofuran, is also reported.The methanolic extract of the plant exhibits antioxidant and radical scavenging activity.... eriobotrya japonicaHabitat: Throughout warmer parts of India.
Ayurvedic: Mayura-shikhaa, Gojihvaa. (Actinopteris dichotoma Bedd. and Celosia cristata Linn. are also used as Mayura-shikhaa. Anchusa strigosa Lebill., and other Boraginaecae sp. are used as Gojihvaa.)Siddha/Tamil: Yaanaichhuvadi.Folk: Mayurjuti, Maaraajuti.Action: Plant—astringent, cardiac tonic, diuretic, mucilaginous, emmolient (used in dysuria, diarrhoea, dysentery. Leaves—
Family: Zingiberaceae.Habitat: Cultivated either as pure plantation crop, or as subsidiary to coffee and arecanut in hilly forests regions of Western Ghats in Karnataka and Kerala, and in parts of Madurai, the Nilgiris and Tirunelveli in Tamil Nadu.
English: Lesser Cardamom.Ayurvedic: Elaa, Sukshmailaa, Kshudrailaa, Bhrngaparnikaa, Tutthaa, Draavidi, Prithvikaa, Triputaa, Truti, Upkunchikaa.Unani: Heel Khurd.Siddha/Tamil: Yelakkai, Ilam.Action: Carminative antiemetic, stomachic, orexigenic, anti-gripe, antiasthmatic, bechic, Oil— antispasmodic, antiseptic. Used for flatulence, loss of appetite, colic, bronchitis, asthma. Paste used as balm for headache, husk for rheumatism.
Key application: In dyspepsia; also as cholagogue. (German Commission E.)The seeds yield an essential oil (611% dry basis). The major constituents are, 1,8-cineole and alpha-terpinylace- tate, with limonene, alpha-terpineol, sabinene and linalool. The seeds contain palmitic and oleic as dominant fatty acids, besides linoleic and linolenic acids, along with alpha-tocopherol, desmosterol and campesterol.The extracts of cardamom cause a significant decrease in gastric secretion after 3 h of treatment. The effect of methanol extract is primarily observed as decreased pepsin output.Terpineol and acetylterpineol, the active principles of cardamom seeds, showed greater penetration enhancing capacities than Azone which was used as a comparative penetration enhancer for the diffusion of Pred- nisolone through mouse skin in vitro.Volatile components exhibit antimicrobial activity. The oil inhibits afla- toxin synthesis.The cardamom seed can trigger gallstone colic (spasmodic pain) and is not recommended for self-medication in patients with gallstone. (German Commission E, PDR, Natural Medicines Comprehensive Database, 2007.)Dosage: Seed of dried fruit—1-2 g powder. (API Vol I.)... elettaria cardamomumHabitat: Throughout warmer regions of India.
English: Euphorbia, Australian Asthma Weed, Pill-bearing Spurge.Ayurvedic: Dudhi, Dudhikaa, Naagaarjuni, Vikshirini.Unani: Dudhi Khurd.Siddha/Tamil: Amman pachharisi.Action: Pectoral, antiasthmatic, antispasmodic. Used for asthma, laryngitis, chronic nasal and bronchial catarrh; diarrhoea, dysentery, intestinal parasitosis Also used in postnatal complaints, failure of lactation. Latex— vermifuge. Used in diseases of urinogenitory tract.
The herb contains several terpenes, anthocyanins, alcohols and steroids. Aerial parts also gave shikimic acid, choline, L-inositol and free sugars.Antiasthmatic activity is attributed to choline and shikimic acid. Shikimic acid and choline showed relaxant and contracting properties on guinea-pig ileum.The aqueous extract of the herb exhibited sedative, anxiolytic, analgesic, antipyretic and anti-inflammatory activities; exerted an inhibitory effect on platelet aggregation.Quercitrin is reported to be responsible for antidiarrhoeal activity.Methanolic extract of the leaves exhibits antibacterial and antifungal activities.Dimeric hydrolysable tannins, eu- phorbains, have been isolated from the plant.... euphorbia hirtaHabitat: Native to tropical Southeast Asia; distributed throughout India; also planted in public parks.
English: Emblic, Indian gooseberry.Ayurvedic: Aaamalaki, Aaamalaka, Dhaatri, Kaayasthaa, Amoghaa, Amritaphala, Amla, Aaamalaa, Dhaatriphala, Vayasyaa, Vrshya, Shiva, Hattha.Unani: Aamalaa, Amlaj.Siddha/Tamil: Nellikkaai, Nelli.Action: Fruit—antianaemic, anabolic, antiemetic, bechic, astringent, antihaemorrhagic, antidiarrhoeal, diuretic, antidiabetic, carminative, antioxidant. Used in jaundice, dyspepsia, bacillary dysentery, eye trouble and as a gastrointestinal tonic. Juice with turmeric powder and honey is prescribed in diabetes insipidus. Seed—antibilious, antiasthmatic. Used in bronchitis. Bark—astringent. Leaf—juice is given in vomiting.
A decoction of powdered pericarp is prescribed for paptic ulcer.Key application: As an antacid. (Indian Herbal Pharmacopoeia.).The fruit is an important source of vitamin C, minerals and amino acids. The edible fruit tissue contains protein concentration threefold and vitamin C (ascorbic acid) concentration 160-fold than those of apple. The fruit also contains considerably higher concentration of most minerals and amino acids than apple.The fruit gave cytokinine-like substances identified as zeatin, zeatin ribo- side and zeatin nucleotide; suspension culture gave phyllembin. Phyllem- bin exhibits CNS depressant and spasmolytic activity, potentiates action of adrenaline and hypnotic action of Nembutal.The leaves contain gallic acid (10.8 mg/g dry basis), besides ascorbic and music acid. The methanol extract of the leaves is found to be effective in rat paw inflammation.The bark contains tannin identified as mixed type of proanthocyanidin.The fruit contains superoxide dis- mutase 482.14 units/g fresh weight and exhibits antisenescent (anti-aging) activity. Fruit, juice, its sediment and residue are antioxidant due to gallic acid. EtOH (50%) extract—antiviral.Aqueous extract of the fruit increases cardiac glycogen level and decreases serum GOT, GPT and LDH in rats having induced myocardial necrosis.Preliminary evidence suggests that the fruit and its juice may lower serum cholesterol, LDL, triglycerides and phospholipids without affecting HDL levels and may have positive effect on atherosclerosis. (Eur J clin Nutr, 42, 1988, 939-944; PhytotherRes, 14, 2000, 592-595.)An aqueous extract of the fruit has been reported to provide protection against radiation-induced chromosomal damage in both pre-and postirradiation treatment. The fruit is reported to enhance natural killer cell activity and antibody dependent cellular cytotoxicity in mice bearing Dalton's lymphoma ascites tumour. The extract of the fruit and ascorbic acid prevented hepatotoxic and nephrotoxic effects induced by lead and aluminium. The toxicity could be counteracted to a great extent by the fruit extract than by an amount of ascorbic acid alone equivalent to that contained in fruits. (The fruit can be used as a dietary supplement to counteract prolonged exposure to metals in population in industrial areas.)The fruits are reported to activate trypsin (proteolytic enzyme) activity.The fruits can be used as coagulant in the treatment of water and can purify low turbidity water.The fruits can be consumed safely all round the year.Dosage: Fresh fruit—10-20 g; pulp juice—5-10 ml. (API Vol. I.)... emblica officinalisHabitat: Throughout India on the hills.
Ayurvedic: Parpata.Unani: Shaahtaraa.Folk: Pittapaaparaa.Action: The plant is used as a substitute for Fumaria parviflora.
A decoction of the herb is used for blood purification and in skin diseases, especially psoriasis.Methanolic extract of the plant exhibits antimicrobial activity against Sarcina subflava.The herb contains several isoquino- line alkaloids which are common to Fumaria officinalis and Fumaria parviflora.Protopine showed smooth muscle relaxant activity in guinea-pigs, rabbits and albino rats and hydrocholeretic activity in anaesthetized dogs. L-tetra- hydrocoptisine showed antipsychotic (neuroleptic) activity in albino rats and mice. Narceimine, narlumidine, adlu- midine and protopine nitrate exhibit anti-inflammatory activity Alkaloids, narlumidine and pro- topine, exhibit significant antifungal activity.... fumaria vaillantiiHabitat: Native to the Mediterranean region; now cultivated mainly in Punjab, Assam, Maharashtra and Vadodara (Gujarat).
English: Fennel. (Poison hemlock has been misidentified as fennel.)Ayurvedic: Mishreyaa, Mishi, Mad- hurikaa, Madhuraa, Shatapushpaa, Shataahvaa. (Shatpushpaa is equated with Saunf and Shataahvaa with Soyaa. Some authors treat these as vice-versa.)Unani: Baadiyaan, Saunf.Siddha/Tamil: Sombu.Action: Carminative, stomachic, antispasmodic, emmenagogue, galactagogue, anti-inflammatory, diuretic. Relieves bloating, nausea, settles stomach and stimulates appetite. Also used in amenorrhoea and enuresis.
Key application: In dyspepsias such as mild, spastic, gastrointestinal afflictions, fullness, flatulence. Fennel syrup or honey can be used for the catarrh of the upper respiratory tract in children. Fennel oil preparations not recommended during pregnancy. (German Commission E, ESCOP, WHO.)German Commission E reported that fennel seed promotes gastrointestinal motility and in higher concentrations acts as antispasmodic. In experiments anethole and fenchone have been shown to have a secre- tolytic action in respiratory tract. The British Herbal Pharmacopoeia and Indian Herbal Pharmacopoeia report its carminative and spasmolytic property.Fennel seed contain about 8% volatile oil (about 50-60% anethole, among others 10-15% fenchone and methyl- chavicol), flavonoids, coumarins (including bergapten) and sterols.The extract of seeds inhibits the growth of micro-organism, especially Streptococcus mutans, that are responsible for dental caries and periodontal diseases.The essential oil from the seed is reported to be antibacterial, antifungal, antioxidant, emmenagogue, oxytocic and abortifacient.The fatty acid, petroselenic acid, obtained from the oil, exhibited antimicrobial activity.Anethole, a major constituent of fennel seed/oil has been found to be an active estrogenic agent with minimal hepatotoxicity and no teratogenic effect.The oil also exhibits anticarcino- genic activity and can be used as a che- moprotective agent.It possesses antioxidant activity close to BHT.Anethole and limonene are used in pharmaceutical compositions for decreasing the side effects of chemotherapy and increasing the immune function.Limonene showed the capacity to inhibit mammary tumours in rats.The boiling water extract of leaves shows hypotensive effect in rats.The methanolic extract of seed showed antispasmodic activity, while aqueous extract accelerated the spontaneous movement of rabbit stomach.Dosage: Dried fruit—3-6 g powder. (API Vol. I.)... foeniculum vulgareHabitat: The Temperate Himalayas.
English: Goosegrass, Clivers, Cleavers, Catch Weed.Action: Choleretic, stomachic, diuretic, refrigerant, lymphatic, alterative, antiscorbutic, detoxifier; non-steroidal anti-inflammatory used for enlarged lymph nodes, especially cervical neck nodes, cystic and nodular changes in the glands, modular goitre. Used as a cleansing drink for malignant conditions and skin disorders, including psoriasis.
Key application: As diuretic. (The British Herbal Pharmacopoeia.)The plant contains iridoid monoter- penes (asperuloside), benzyl isoquino- line alkaloids (including protopine), beta-carbolin alkaloids (including harmine), quinazoline alkaloids and fla- vonoids (such as luteolin). Methanolic extract of the plant contains chloro- genic acid, scopoletin and rutin. The plant is reported to contain several sterols. The root contains anthraqui- nones.Asperuloside can be chemically converted to prostanoid intermediates.... galium aparineHabitat: Punjab, Rajasthan, Gujarat, Andhra Pradesh and Tamil Nadu.
English: Tamthar.Siddha/Tamil: Kullai.Folk: Dhohan (Rajasthan), Jalidar (Punjab), Kharamati (Maharashtra).Action: Root—antidiarrhoeal. Root and bark—used in genitourinary infections, syphilis and smallpox.
The methanol extract of the roots contain beta-carboline alkaloids, harman, harmine, harmol, harmalol and harmaline.The roots are also used to treat cough.... grewia villosaHabitat: Dry forests of Deccan Peninsula, Central India and parts of Uttar Pradesh and Bihar.
Ayurvedic: Anjana.Siddha/Tamil: Katudugu, Kodapalai.Action: Balsam—used for sexually transmitted diseases. The balsam is similar to Copaiba balsam (Copaifera langsdorffii Desf., Leguminosae) of Brasil and is used in leucorrhoea, chronic cystitis, gonorrhoea, combined with cubebs and sandal. The resin (not the oleo-resin) is used as diuretic.
The essential oil of H. binata is not a substitute for Copaiba oil.The methanolic extract of the heart- wood yields beta-sitosterol, (+)-taxifo- lin, eriodictyol, (+)-catechin, (+)-epi- catechin and (+)-mopanol. The phenolic compounds are said to impart antibacterial and antifungal property to the herb.The bark has a good absorption capacity for mercury from water.... hardwickia binataHabitat: North-west Himalayas at 2,350-5,000 m.
English: Seabuckthorn, Sand Thorn.Folk: Dhurchuk, Chumaa, Tarwaa (Uttar Pradesh), Sirmaa (Punjab, Ladakh).Action: Fruit—astringent, anti- diarrhoeal, stomachic, antitussive, antihaemorrhagic.
Sea Buckthorn preparations are used internally for stomach ulcer, duodenal ulcer and other illnesses of the alimentary organs; externally in cases of burns, bedsores and other skin complications induced by the treatment with X-rays and other radiations.The berries contain polyphenols, 3,4-dihydroxy benzoic acid and p- coumaric acid. They are an important source of vitamins for people living in cold, long winter regions; contain high concentration of vitamin A (carotene 30-40 mg), B1, B2, B6, C (50-600 mg) and E (160 mg/100 g).The plant is an effective antioxidant and shows protective effect on smooth muscles of rabbits in vitro. The methanolic extract of the berry showed scavenging activity on chemically generated superoxide radicals.The leaves contain flavonoids, iso- rhamnetin and astragalin; the bark gave serotonin.... hippophae rhamnoidesHabitat: Native to China. Fruits imported from China and IndoChina.
English: Star Anise, Chinese Anise, Aniseed Stars.Unani: Baadyaan Khataai.Siddha/Tamil: Takkola, Anasippo.Folk: Anasphal.Action: Carminative (used for colic), stimulant, diuretic. Also used in rheumatism.
Key application: In catarrhs of the respiratory tract and peptic discomforts. (German Commission E.)The fruit contains a volatile oil containing trans-anethole 80-90%, and feniculin (14.56%), with estragole, beta-bisabolene, beta-farnesene, ca- ryophyllene, nerolidol.The intake of trans-anethole (1.0%) does not show any chronic toxicity in rats. Veranisatins, isolated from the extract, showed convulsive effect in mice. Methanolic extract exhibited a hypothermic effect in mice.Illicium griffithii Hook. f. & Thoms. is found in Bhutan and Khasi hills at altitudes of 1,400-1,100 m. The fruit, known as Baadiyaan, is bitter and astringent, reported to be poisonous. It is used as stimulant and carminative. Essential oil resembles that from aniseed (Pimpinella anisum Linn.) and fennel (Foeniculum vulgare Mill.)... illicium verumHabitat: Cultivated in plains throughout India.
English: Garden Balsam. (Balsam Apple is not related to Impatiens. It is the fruit of Momordica balsamina.)Ayurvedic: Tarini (provisional synonym).Unani: Gul-menhdi.Siddha/Tamil: Kasittumbai.Action: Cathartic, diuretic, antirheumatic. Flowers—used in burns and scalds.
The plant is reported to contain cyanochroic constituents, antibacterial substances and an alkaloid. The seeds contain the triterpenoid hosenkol A, the first baccharance triterpenoid from natural source. The seeds also contain a protein-associated amyloid, galac- toxyloglucan and beta-sitosterol.In China, the aerial parts are used for the treatment of articular rheumatism. In Korea, the plant is used for treating tuberculosis. In Brunei, a decoction of the root is given in irregular menstruation. In Japan, the juice, obtained from the white petals, is applied topically to treat several types of dermatitis, including urticaria.The flowers contain flavonols, flavo- noid pigments, phenolic compounds and quinones.An ethanolic extract (35%) of flowers shows significant anti-anaphylactic activity in mice.The methanolic extract of the whole plant exhibited strong antibacterial activity against Bacillus subtilis and Salmonella typhimurium; antibacterial and antifungal activity has been attributed to a naphthoquinone derivative.... impatiens balsaminaHabitat: Native to Europe and North America. Distributed in Western Himalayas from Kumaon westwards at 1,700-4,200 m.
English: Common Juniper.Ayurvedic: Hapushaa, Havushaa, Haauber, Matsyagandha.Unani: Abahal, Haauber, Hubb-ul- arar, Aarar.Action: Berries—diuretic, urinary antiseptic, carminative, digestive, sudorific, anti-inflammatory, emmenagogue. Used for acute and chronic cystitis, renal suppression (scanty micturition), catarrh of the bladder, albuminuria, amenorrhoea, leucorrhoea. Aerial parts—abortifacient.
Key application: In dyspepsia. (German Commission E.) Juniper berry may increase glucose levels in diabetics. (ESCOP.) As a diuretic.(The British Herbal Pharmacopoeia.)The Ayurvedic Pharmacopoeia of India recommends the dried fruit in malabsorption syndrome.Animal studies have shown an increase in urine excretion as well as a direct effect on sooth muscle contraction. (German Commission E, ESCOP.)Con- traindicated in kidney disease. (Sharon M. Herr.)(In Kerala, Hapushaa and Mundi are considered to be synonyms; Syphaer- anthus indicus,Asteraceae, is used as Hapushaa.)The major constituents of the volatile oil are alpha-pinene, sabinene and alpha-terpinene. Methanolic extract of the plant gave several labdane diter- penoids and diterpenes. The leaves contain the biflavones, cupressufla- vone, amentoflavone, hinokiflavone, isocryptomerin and sciadopitysin. The berries also contain condensed tannins. Seeds gave haemagglutinin.Juniperus recurva Buch-Ham ex D. Don, syn. J. excelsa auct. non-Bieb. (temperate Himalaya from Kashmir to Bhutan) is known as Weeping Blue Juniper. J. macropoda Boiss. (the Himalaya from Nepal onwards) is known as Himalayan Indian Juniper. Both the species are used like J. communis var. saxatillis.The berries gave a diterpene ketone, sugrol, beta-sitosterol glucoside and 10-nonacosanol.Plant extract can be used in toothpastes and mouth-rinses to reduce dental plaque and bleeding.Dosage: Dried fruit—2-6 g powder. (API, Vol. III.)... juniperus communisHabitat: Throughout the warm and moist parts of India, especially abundant in West Bengal.
Ayurvedic: Parnabija, Pattharchuur, Pattharchat, Hemsaagar. (Paashaa- nabheda is a misleading synonym.)Unani: Zakhm-e-Hayaat.Siddha/Tamil: Runakalli.Action: Leaf—anti-inflammatory, antifungal, antibacterial. Applied to wounds, burns, boils, swellings.
The methanolic extract of leaves exhibited potent anti-inflammatory activity against both exudative and proliferative phases of inflammation. The leaf extract also showed analgesic activity.The leaves gave flavonoids—querce- tin, kaempferol, quercetin-3-diarabi- noside andkaempferol-3-glucoside; also n-hentriacontane, n-tritriacontane, alpha- and beta-amyrin and sitosterol; p-coumaric, ferulic, syringic, caffeic and p-hydroxybenzoic acids.... kalanchoe pinnataHabitat: Native to South Africa. Planted in forest nurseries and plantation at Pune and Vada (Maharashtra).
English: African Mahogany.Action: Anti-inflammatory, cardiogenic.
Methanolic extract of the stem bark showed cardiovascular (cardiogenic) effect in rodents by increasing blood pressure and vasoconstriction of the arota partly due to the stimulation of beta-receptors and alpha-adreno- ceptors.Alcoholic extract of the stem bark showed anti-inflammatory activity... khaya senegalensisHabitat: Native to eastern United States; imported into India.
English: Indian Tabacco, Pukeweed.Ayurvedic: Devanala (var.).Action: Antiasthmatic, antispasmodic, broncho-dilator, expectorant, mild sedative and relaxant. Used as a tabacco deterrent (as a major ingredient in many antismoking mixtures).
Key application: In the treatment of asthma, bronchitis. (German Commission E.) As respiratory stimulant. (The British Herbal Pharmacopoeia.)Lobelia contains piperidine alkaloids, mainly lobeline, with lobelanine, lobelanidine, norlobelanine, isolobi- nine. Lobeline stimulates respiration in animals by stimulating respiratory centre and at high doses stimulates the vomiting centre.Lobeline has similar but less potent pharmacological properties to nicotine but 1/20-1/5 as potent.Lobeline (0.5%) has also been used as an active ingredient in skin-lightening preparations.Clinical research could not demonstrate lobeline efficacy greater than placebo in smoking cessation. It was disallowed as an ingredient in antismoking products in the US in 1993. (Natural Medicines Comprehensive Database, 2007.)The leaves contain beta-amyrin pal- mitate which possesses sedative and antidepressant properties comparable to the antidepressant drug mianserin. Methanolic extract of leaves exhibited antidepressant activity.The leaf powder is toxic at 0.6-1.0 , (Francis Brinker.)... lobelia inflataMethyl alcohol, or wood spirit (see METHANOL), is distilled from wood and is thus a cheap form of alcohol. It has actions similar to, but much more toxic than, those of ethyl alcohol. It has a specially pronounced action on the nervous system, and in large doses is apt to cause neuritis, especially of the optic nerves, leading to blindness, partial or complete.... methyl
Habitat: West Bengal, eastern Assam, as a weed in tea gardens; sal and other forests and waste lands. Distributed in tropical America, Africa and Asia.
Folk: Mikaaniaa.Action: Root—anti-inflammatory, hepatoprotective, adaptogenic.
Stigmasterol, beta-sitosterol and sesquiterpene dilactones, mikanolide, dihydromikanolide, deoxymikanolide and scandenolide have been isolated from the weed.The root extract exhibited anti-inflammatory activity; reduced carra- geenan-induced paw oedema in experimental rats.The methanolic extract of the root showed CNS deperssant action. It showed reduction in spontaneous motility, hypothermia, potentiation of pentobarbitone sleeping time, analgesia, suppression of aggressive behaviour and antagonism to amphetamine toxicity on experimental animals.The methanolic extract of the root exhibited adaptogenic activity against a variety of stress-induced effects in albino rats.The chemoprotective, anticarcino- genic and hepatoprotective effect of the methanolic extract of the root were also evaluated in animal studies. Chemical carcinogens were reduced in the liver of rats treated with the plant extract. The root extract induced recovery from carbon tetrachloride-induced damage to liver tissues in mice.... mikania cordataHabitat: Native to China; cultivated in Punjab, Uttar Pradesh, Kashmir and North-Western Himalayas. English: Chinese White-Mulberry. Unani: Shahtuut, Tuut.
Action: Fruit—cooling, mild laxative. Used for sore throat, dyspepsia and melancholia. Leaves and root bark—expectorant, diuretic, hypotensive. Bark extract—hypoglycaemic. Leaf— anti-inflammatory, emollient, diaphoretic. Used as a gargle in inflammations of the throat.
The plant is rich in phenolics. The leaves gave flavonoids (including rutin, moracetin); anthocyanins (cyanidin and delphinidin glucosides); artocarpin, cycloartocarpin and analogues. The root bark contained fla- vonoids including the kuwanons, san- gennons, mulberrosides and mulber- rofurans.Hot water extract of the dried mulberry leaves fed to rabbits on 1% cholesterol diet exhibited significant hypolip- idaemic or hypocholesterolaemic effect. In addition, suppression of hepatic enlargement and fat deposition in the hepatic cells was also observed.An aqueous methanol extract of the root bark significantly reduced plasma sugar levels in mice.The extract also showed anti-inflammatory and antipyretic activity in exudative, proliferative and chronic phases of inflammation.Aqueous and alkali extracts of leaves and stems are active against GramPositive bacteria and yeast.... morus albaHabitat: Throughout India; grown in houses, gardens and temples.
English: Holy Basil, Sacred Basil.Ayurvedic: Tulasi, Surasaa, Surasa, Bhuutaghni, Suravalli, Sulabhaa, Manjarikaa, Bahumanjari, Deva- dundubhi, Apet-raakshasi, Shuu- laghni, Graamya, Sulabhaa.Unani: Tulasi.Siddha/Tamil: Tulasi, Nalla-Tulasi.Action: Leaf—carminative, stomachic, antispasmodic, antiasthmatic, antirheumatic, expectorant, stimulant, hepatoprotective, antiperiodic, antipyretic and diaphoretic. Seed— used in genitourinary diseases. Root—antimalarial. Plant—adap- togenic, antistress. Essential oil— antibacterial, antifungal.
The Ayurvedic Pharmacopoeia of India recommends the use of the leaf and seed in rhinitis and influenza; the seed in psychological disorders, including fear-psychosis and obsessions.Major components of the essential oil are eugenol, carvacrol, nerol and eugenolmethylether. Leaves have been reported to contain ursolic acid, api- genin, luteolin, apigenin-7-O-glucu- ronide, luteolin-7-O-glucuronide, orientin and molludistin.Ursolic acid, isolated from leaves, exhibited significant protection of mast cell membrane by preventing granulation and decreased histamine release. The ethanolic extract (50%) of fresh leaves, volatile oil from fresh leaves and fixed oil from seeds showed antiasth- matic activity and significantly protected guinea-pigs against histamine and dyspnoea. They also showed anti- inflammatory activity against carrage- enan-, serotonin-, histamine- and PGE-2-induced inflammation and inhibited hind paw oedema in rats.The ethanol extract (90%) of the leaves showed hepatoprotective effect against paracetamol-induced liver damage.The plant extract exhibited antiul- cerogenic property against experimental ulcers.Oral administration of alcoholic extract of leaves lowers blood sugar level in normal, glucose-fed hyperglycaemic and streptozotocin-induced diabetic rats. The activity of the extract was 91.55 and 70.43% of that of tolbutamide in normal and diabetic rats respectively.Administration of the juice of the plant affected a significant reduction in the size of urinary brushite crystals.A study of methanol extract and aqueous suspension of the leaves showed immunostimulation of humoral immunologic response in albino rats indicating the adaptogenic action of the plant.Dosage: Seed—1-2 g powder (API, Vol. IV); plant—50-10 ml infusion (CCRAS.).... ocimum sanctumHabitat: Throughout the Himalayas up to an altitude of about 3,500 m, and in the hills of Assam.
English: Perilla, Wild Coleus.Folk: Bhanjeer, Ban-tulasi, Ban- jiraa, Bhasindi.Action: Herb—sedative, antispasmodic, antiasthmatic, resolvent.
P. frutescens var. crispa is used in mixtures prescribed for cough and lung affections.Several chemotypes of Perilla have been detected. The Indian type is rich in rosefuran. Other components are perillene, perilla ketone, beta-caryo- phyllene, phellandrene and a few ses- quiterpenoids. Aerial parts gave ethyl linolenate, linolenic acid and beta- sitosterol. The leaves also gave an an- thocyanin, perillanin. The leaves and flowering tops yield essential oils containing perilla ketone as major com- ponent—94% in leaf oils and 47% in inflorescence oils at fruiting stage.Perillaldehyde, a major component of the plant extract, inhibits (moderately) a broad range of both bacteria and fungi. The MeOH extract of var. acuta Kudo is reported to prolong hexobarbital-induced sleep in mice. Dillapiol has been isolated as the active principle from the methanolic extract.... perilla frutescensHabitat: The Himalayas, from Kashmir to Kumaon up to an altitude of 4,000 m.
English: Common Reed.Folk: Dila, Dambu (Punjab).Action: Rhizomes and roots—diuretic, emmenagogue, diaphoretic, hypoglycaemic, antiemetic.
The rhizomes are rich in carbohydrates; contain nitrogenous substances 5.2, fat 0.9, N-free extr. 50.8, crude fibre 32.0, sucrose 5.1, reducing sugars 1.1, and ash (rich in silica) 5.8%; as- paragine 0.1% is also present. Leaves possess a high ascorbic acid content (200 mg/100 g).Nodes and sheaths yield 6.6% and the underground parts over 13% of furfural.The root of common Reed is prescribed in Chinese traditional medicine as an antipyretic against influenza and fevers. Presence of polyols, betaines and free poline has been reported in the methanolic extract. The extract is reported to show bactericidal activity. The root gave a polysaccha- ride which contains sugars, arabinose, xylose and glucose in a molar ratio of 10:19:94; some ofthe fractions showed immunological activity.... phragmites communisHabitat: Sundarbans, in salt marshes and mangrove swamps.
Folk: Kukarondh, Manjurukh (Bengal).Action: Root and leaves—astringent, antipyretic; given in decoction as a diaphoretic in fevers. Leaf— juice is given for dysentery; an infusion for lumbago, also against leucorrhoea. Root—antiinflammatory, hepatoprotective.
The aerial parts contain terpenic glycosides. The root contains sesqui- terpenes, lignin glycosides, thiophene derivatives.The extracts of defatted roots showed significant anti-inflammatory activity. The extracts inhibited protein exudation and leucocyte migration.Neuropharmacological studies on different experimental models of rodents exhibited potent central nervous system depressant activity.The methanolic fraction of the extract exhibited significant hepatopro- tective activity against induced hepa- totoxicity in rats and mice. The extract also caused significant reduction in the elevated serum enzyme levels and serum bilirubin content in acute liver injury.... pluchea indicaHabitat: Punjab, Upper Gangetic plains, Gujarat, Rajasthan.
Ayurvedic: Raasnaa, Rasanaa, Raas- nikaa, Rasaa, Yuktaa, Yuktrasaa, Suvahaa, Elaaparni.Folk: Vaaya-surai (Uttar Pradesh), Raayasan.Action: Aerial parts—smooth muscle relaxant. Stem—antiinflammatory. Pluchea lanceolata is the source of Raasnaa in Punjab, Uttar Pradesh and Gujarat. Vanda roxburghii is used as Raasnaa in Bengal. Throughout South India, Alpinia galanga is accepted as Raasnaa.
The stem and leaves contain morete- nol, moretenol acetate, neolupenol, oc- tacosanoic, hexacosanoic and tetra- cosanoic acid, tetracosanol, hexaco- sanol, triacontanol, stigmasterol and beta-sitosterol-D-glucoside.The petroleum extract of the stem and leaves and the chloroform-soluble portion of the methanolic extract exhibited 31.9% and 54.5% antioedema activity, respectively. The triterpenes, moretenol acetate, moretenol and ne- olupenol exhibited 55.2,32,8 and 39.7% anti-inflammatory activity respectively as against ibuprofen as standard exhibiting 65.5% activity.... pluchea lanceolataHabitat: From Kashmir to Kumaon.
English: Knotgrass, Knotweed, Mexican Sanguinaria.Folk: Machoti, Kesri.Action: Astringent and haemostatic. Used for excessive menstruation, bleeding piles; bleeding from bowel, stomach, lungs, nose, throat; mucous colitis, children's summer diarrhoea.
Key application: In mild catarrhs of the respiratory tract, inflammatory changes to the oral and pharyngeal mucosa. (German Commission E.)The plant gave flavonoids including quercetin, avicularin, quercitrin, and derivatives of kaempferol, esculetin and scopoletin. The plant also gave gallic, caffeic, oxalic., silicic, chloro- genic and p-coumaric acids; tannins including catechin.The methanolic extract of the plant showed high protection against CCl4- induced hepatotoxicity in mice. This activity is attributed to the presence of flavonoid glucosides.The flavonoids exhibit astringent properties and are found to decrease capillary fragility and have a cortisonelike-effect on gingival tissue. (J Ethno- pharmacol, 74(1), 2001.)... polygonum aviculareHabitat: Throughout India in marshy places, up to 1,900 m. in the hills.
Ayurvedic: Rakta-rohidaa (Gujarat).Siddha/Tamil: Attalaree.Action: Plant juice and rootstock— used in pneumonia, consumption, jaundice, fevers. Leaf— antispasmodic. Used for colic.
The leaves contain flavonoids— quercetin, rhamnetin, quercitrin, avic- ularin and rutin. Flowers contain pigments, delphinidin-3,5-diglucoside and cyanidin-3,5-diglucoside and quercetin.The methanolic aqueous extract of the leaf gave a pure anthelmintic substance, a terpenoid (PGA). (The herb is used as an anthelmintic in Sudan.)... polygonum glabrumHabitat: Native to Central America; cultivated chiefly in Uttar Pradesh, Punjab, Bihar, Maharashtra, and Andhra Pradesh.
English: GuavaAyurvedic: Peruka (non-classical), Amaruuda.Siddha/Tamil: Koyya.Action: Unripe fruit—antidiar- rhoeal. Leaves—used for dysentery, diabetes, cough and cold. Flowers— anthelmintic.
Guava juice may be helpful in regulating blood sugar in type 2 diabetes and syndrome X. (Sharon M. Herr.)A residue obtained from methanolic fraction of unripe fruits was found to possess significant antidiarrhoeal activity. The fraction decreased gastric motility in an experimental animal model. The fraction was also found to inhibit significantly the growth of different strains of Shigella sp. and Vibrio cholerae.In China and Taiwan, the leaf extract is administered for treating diarrhoea, dysentery, diabetes and inflammations. The leaf extract (containing quercetin) inhibits acetylcholine release in the gastro-intestinal tract which might account for us antidiarrhoeal activity. An extract of leaves with a little salt is given in relieve whooping cough.In New Papua Guinea, decoction of new leaf tips is drunk to treat hepatitis.Guava seed oil contains very higher proporation of linoleic acid (75.52%) than sunflower, groundnut, olive, soybean and coconut oil. The seeds from Pakistan yield 9.25% of a fatty oil.Vitamin C content of the ripe fruit ranges from 100 to 1000 mg/100 g. It is highest in the skin and in the flesh next to it.Psidium cattleyanum Sabine is equated with Straberry Guava and is known as Seemai Koyya in Tamil Nadu and Pahari Payaar in Bengal. The fruit contains vitamin C 15-44 mg/100 g.Smaller var. of Guava is equated with Psidium guineense Sw. It is found in Tripura.... psidium guajavaHabitat: Throughout the tropical zones of India in the hilly regions.
English: Indian Kino tree, Malabar Kino tree.Ayurvedic: Asana, Bijaka, Priyaka, Pitashaala.Unani: Bijaysaar.Siddha/Tamil: Vengai.Action: Bark-kino—astringent, antihaemorrhagic, antidiarrhoeal. Flowers—febrifuge. Leaves—used externally for skin diseases.
Key application: Heartwood— in anaemia, worm infestation, skin diseases, urinary disorders, lipid disorders and obesity. Stem bark—in diabetes. (The Ayurvedic Pharmacopoeia of India.)The heartwood and roots contain isoflavonoids, terpenoids and tannins. Tannins include the hypoglycaemic principle (-)-epicatechin. Stilbenes, such as pterostilbene; flavonoids, including liquiritigenin, isoliquiritige- nin, 7-hydroxyflavanone, 7,4-dihy- droxyflavanone, 5-deoxykaempferol and pterosupin; a benzofuranone mar- supsin and propterol, p-hydroxy-ben- zaldehyde are active principles of therapeutic importance.The gum-kino from the bark provides a non-glucosidal tannin, Kino tannic acid (25-80%).The (-)-epi-catechin increases the cAMP content of the islets which is associated with the increased insulin release, conversion of proinsulin to insulin and cathepsin B activity.Oral administration of ethylacetate extract of the heartwood and its fla- vonoid constituents, marsupin, ptero- supin and liquiritigenin, for 14 consecutive days to rats exhibited a significant reduction of serum triglycerides, total cholesterol and LDL- and VLDL-cholesterol levels, but it did not exert any significant effect on HDL- cholesterol.The ethanolic and methanolic extracts of the heartwood exhibited significant in vitro antimicrobial activity against Gram-positive and Gramnegative bacteria and some strains of fungi.Kino is powerfully astringent. The therapeutic value of kino is due to Kino tannic acid.Dosage: Heartwood—50-100 g for decoction. (API, Vol. I); stem bark—32-50 g for decoction (API, Vol. III).... pterocarpus marsupiumHabitat: Native to India; cultivated throughout India.
English: Eggplant, Brinjal.Ayurvedic: Bhantaki, Bhantaa, Vaartaaka, Vaartaaku, Vaartaakini, Vrintaaka.Unani: Baingan.Siddha/Tamil: Kathirikai.Folk: Baingan, Bhantaa.Action: Fruit—recommended in liver complaints and for amenorrhoea. The fruit is reported to stimulate the intrahepatic metabolism of cholesterol, produces a marked drop in blood cholesterol level. Aqueous extract of fruit is reported to inhibit choline esterase activity of human plasma. Root—anti- asthmatic. Leaves—toxic; used mostly externally for the treatment of burns, cold sores and abscesses. Seeds—anticholesterolemic.
Steroidal saponins, melongosides were isolated from seeds; tigogenin, diosgenin were also obtained. Querce- tin, 3-O-rhamnoside and kaempferol- 3-O-rutinoside have been isolated from the leaves. The ethanol extract (80%) showed anti-inflammatory activity in paw oedema and cotton pellet method in rats. Crude extract of fruits showed diuresis and dose-dependent hypotensive response in normotensive rats. Ether-soluble methanolic extract exhibited strong inhibitory activity on lipoxygenase, involved in atherosclerotic processes and platelet aggregation in rats.Solanum melongena Linn. var. incanum Kuntze, synonym S. coagulans Forsk. is known as Bana-bhantaa (also a synonym of Solanum ferox) and is used as Brihati in Kerala. Air-dried fruits and leaves from coimbatore contain 1.05 and 0.97% of alkaloids respectively. The fruits contain solaso- dine, campesterol and beta-sitosterol. Solamargine, solasodine, ursolic acid and its derivatives exhibited significant cytotoxic effects against human P2C/PRF/5 cells in vitro.... solanum melongenaHabitat: Cultivated in many parts of India.
English: Rose Apple.Ayurvedic: Raaj-Jambu. (Fruits— pale yellow or pinkish white).Siddha/Tamil: Peru Navel.Folk: Gulaabjaamun.Action: Fruit—used in liver complaints. Bark—astringent, antidiarrhoeal, antidysenteric. Leaves—astringent, anti-inflammatory.
The juice of fresh fruit contains alanine, aspartic acid, cystine or cysteine, glutamine, threonine and tyrosine. The essential oil, obtained from leaves, is a good source of dl-alpha-pinene (2684%) and l-limonene (23-84%).Ethyl acetate and methanolic extract of the leaves are very effective in curing pedal oedema and in acute and chronic swelling; also gave encouraging results in arthritis. Though all extracts (methanolic, hexane, dichloromethane and ethyl acetate) of the leaves exhibit anti-inflammatory activity, a 10% aqueous extract of the leaves is found significantly effective when compared to 80 mg/kg of phenylbutazone.In Brazil, a decoction of dry leaves is given in diabetes.Aerial parts exhibit diuretic activity.... syzygium jambosHabitat: From Uttar Pradesh to West Bengal, extending southwards to Kerala.
Ayurvedic: Raasnaa (used in Eastern India). Pluchea lanceolata is the accepted source of Raasnaa.Throughout South India Alpinia galanga is used as Raasnaa.Folk: Baandaa-Raasnaa.Action: Roots—antipyretic, antiinflammatory, tranquilizer, tonic to liver, laxative. Used in rheumatism, lumbago, inflammations; diseases of the nervous system; diseases of the abdomen, dyspepsia; bronchitis, chest diseases. Roots form a constituent of medicated oils, used externally on rheumatic swellings and neurological affections. Root is also used in the treatment of fractures.
Petroleum ether, chloroform and methanol extracts of the root showed anti-inflammatory activity in rats. Ethanolic extract of the root also showed hepatoprotective activity in albino mice.The root yielded tetracosyl feru- late and beta-sitosterol D-glucoside. Petroleum ether, chloroform and methanol extracts of the root showed 54.3, 42.1 and 21.9% anti-inflammatory activity at a dose of 0.5 g/kg in rats. Heptacosane, octacosanol and traces of their higher homologues, a bitter principle, saponin, beta-sitosterol and tannins were isolated from the plant.... vanda roxburghiiHabitat: Mediterranean region; South-West Asian countries, up to Pakistan. (Seeds are imported from Iran.)
English: Monk's Pepper-tree, Hemp tree.Ayurvedic: Renukaa (seed). Renukaa and Harenukaa are synonyms in Indian medicine.Unani: Sambhaalu.Action: Dried ripe fruit—acts on the anterior pituitary gland, reducing FSH and increasing LSH; stimulates production of progesterone by reducing oestrogen; used as a substitution therapy in primary and secondary corpus luteum deficiency. Used for premenstrual syndrome, for regulating hormones in amenorrhoea and for bleeding between periods; also as a galactagogue and to assist bust development.
The herb is also used in the treatment of premature old age due to sexual excess, nervous debility and impotence (as a homoeopathic drug). Vitex agnus extract is found to lower prolactin levels in men (the decrease in prolactin levels results in improved sexual performance. Males with hyperprolacti- naemia frequently face impotence).Key application: In irregularities of menstrual cycle, premenstrual complaints, mastodynia. (German Commission E.) As a hormonal modulator. (The British Herbal Pharmacopoeia.)The methanolic extract of the flowering stems of Vitex agnus-castus yielded iridoids, angnucastoside-A, B and C, in addition to aucubin, agnuside, mussaenosidic acid and 6'-O-p-hy- droxybenzoylmussaenosidic acid, and phenylbutenone glucoside, myzoden- drone.Dopaminergic compounds, present in the herb, are clinically important compounds which improve premenstrual mastodynia and other symptoms of premenstrual syndrome.The herb may counteract birth control pills. (Sharon M. Herr.)... vitex agnus-castusHabitat: Bengal, Assam, Konkan, and Tamil Nadu.
Ayurvedic: Bhringaraaja (yellow- flowered var.), Pitabhringi, Pitabhringa-raaja, Avanti, Ke- sharaaja, Kesharaaga.Siddha/Tamil: Manjal karisaalai, Potralai kaiyan tagarai, Patalai Kaiantakerai.Action: Leaves—bechic; used in alopecia, juice used for dyeing hair and for promoting hair growth. Plant—deobstruent; used in menorrhagia and abdominal swellings, as a tonic for hepatic and splenic enlargement.
See Eclipta alba.The expressed juice of the herb contained an oil-soluble black dye 11.2; tannin 220; saponin 500 (contradictory reports) and phytosterol 3.75 mg/100 g among other constituents. The leaves contain isoflavonoids.The bisdesmosidic oleanolic acid saponins have been isolated from the fresh leaves. Significant hepatoprotec- tive activity has been found in the pro- saponin from ginsenoside Ro (chiku- setsusaponinV); and in coumestans, wedelolactone and demethyl wedelo- lactone, isolated from the methanol extract of the herb.Wedelolactone has also been found to be a potent and selective 5-lipoxy- genase-inhibitor, the process being an oxygen radical scavenger mechanism.Wedelolactone (0.05%), isolated from the leaves, is analogous in structure to coumestrol, an estrogen from Melilotus sp. (clover).Family: Rubiaceae.Habitat: Sub-Himalayan region, West Bengal, Madhya Pradesh, Andhra Pradesh and Maharashtra.
Ayurvedic: Tilaka.Folk: Tiliyaa (Bihar), Tilki, Mimri (Bengal).Action: Bark—administered in urinary affections.... wedelia calendulaceae
Habitat: Throughout the drier and subtropical parts of India.
English: Winter Cherry. (Physalis alkekengi is also known as Winter Cherry.)Ayurvedic: Ashwagandhaa, Haya- gandhaa, Ashwakanda, Gandharva- gandhaa, Turaga, Turagagandhaa, Turangagandhaa, Vaajigandhaa, Gokarnaa, Vrishaa, Varaahakarni, Varadaa, Balyaa, Vaajikari. (A substitute for Kaakoli and Kshira- kaakoli.) Cultivated var.: Asgandh Naagori. (Indian botanists consider the cultivated plants distinct from the wild ones.)Unani: Asgandh.Siddha: Amukkuramkizhangu.Action: Root—used as an antiinflammatory drug for swellings, tumours, scrofula and rheumatism; and as a sedative and hypnotic in anxiety neurosis. Leaf— anti-inflammatory, hepatopro- tective, antibacterial. Fruits and seeds—diuretic. Withanine— sedative, hypnotic. Withaferin A—major component of biologically active steroids; as effective as hydrocortisone dose for dose. Antibacterial, antitumour, an- tiarthritic, significantly protective against hepatotoxicity in rats.
The root contains several alkaloids, including withanine, withananine, withananinine, pseudo-withanine, somnine, somniferine, somniferinine. The leaves of Indian chemotype contain 12 withanolides, including withaferin A. Steroidal lactones ofwithano- lide series have been isolated.Withanine is sedative and hypnotic. Withaferin A is antitumour, an- tiarthritic and antibacterial. Anti-inflammatory activity has been attributed to biologically active steroids, of which withaferin A is a major component. The activity is comparable to that of hydrocortisone sodium succinate.Withaferin A also showed significantly protective effect against CCl4- induced hepatotoxicity in rats. It was as effective as hydrocortisone dose for dose.The root extract contains an ingredient which has GABA mimetic activityThe free amino acids present in the root include aspartic acid, glycine, tyrosine, alanine, proline, tryptophan, glutamic acid and cystine.The Ayurvedic Pharmacopoeia ofIn- dia recommends Ashwagandha in im- potency. This claim could not be sustained in a recent experiment and raises a doubt about the equation of classical Ashwagandha with Withania somnifera. A methanolic extract of With- ania somnifera root induced a marked impairment in libido, sexual performance, sexual vigour and penile dysfunction in male rats. (Llayperuma et al, Asian J Androl, 2002, 295-298.)The total alkaloids of the root exhibited prolonged hypotensive, brady- cardiac and depressant action of the higher cerebral centres in several experimental animals.A withanolide-free aqueous fraction isolated from the roots of Withania somnifera exhibited antistress activity in a dose-dependent manner in mice. (Phytother Res 2003, 531-6.)(See also Simon Mills; American Herbal Pharmacopoeia, 2000; Natural Medicines Comprehensive Database, 2007.)Dosage: Root—3-6 g powder. (API, Vol. I.)... withania ashwagandhaHabitat: Meghalaya, foothills of Assam and Peninsular India.
Ayurvedic: Tumburu (Kerala), Ashvaghra, Tejabala.Siddha/Tamil: Tratechai.Action: Fruits—used for diarrhoea, dyspepsia; asthma, bronchitis; rheumatism; diseases of the mouth and teeth. Pericarp—astringent, digestive, stimulant. Essential oil—disinfectant, used in infective dermatosis. Bark—cholinergic, diuretic, hypoglycaemic, spasmolytic. Root—emmenagogue, febrifuge.
The trunk-bark from Assam gave alkaloids—chelerythrine (0.014%), evodiamine (0.03%) and hydoxyevodi- amine (0.05%). The essential oil from the fruit contains l-sabinene, alpha- terpinene, beta-phellandrene, 1,4-cine- ole, decanal, octanal, terpinen-4-ol, dihydrocarveol, l-cryptone and cumi- naldehyde.The essential oil exhibits anti-inflammatory, anaesthetic and antago- nisic activity.Z. nitidum (Roxb.) DC. (Bihar eastwards to Sikkim and Assam) is known as Tezmul in Assam. The root is used in toothache and stomachache.The plant is used as one of the ingredients in the preparation of pharmaceutical tablets given to drug addicts for the treatment of withdrawl symptoms.Methanolic extract of the roots gave nitidine, chelerythrine and isogari- dine. The extract showed antitumour property.Z. ovalifolium Wight (Eastern Himalayas, Meghalaya, the Western Ghats of South Kanara and Kerala) is known as Armadalu in Karnataka and Diang-shih in Meghalaya (Khasi Hills). The leaf contains diosmetin and the heartwood contains flavonoids of dihydrofisetin and cinnamaldehyde. The bark and fruit possess properties similar to other species of the genus.... zanthoxylum budrunga
Health Encyclopedia