Premedication Health Dictionary

Premedication: From 3 Different Sources


The term applied to drugs given, often by injection, 1–2 hours before an operation to prepare a person for surgery. Premedication usually contains a opioid analgesic drug and often an anticholinergic drug.
Health Source: BMA Medical Dictionary
Author: The British Medical Association
A drug or drugs given to a patient to produce sedation before an operation, whether this is done under a local or general anaesthetic. A narcotic analgesic drug (see NARCOTICS; ANALGESICS) is usually used, as this relieves pain as well as anxiety. An antisecretory drug is often added to reduce the secretions in the airways and thus lessen the risk associated with general anaesthesia. Premedication reduces the amount of anaesthetic needed to make the patient unconscious.
Health Source: Medical Dictionary
Author: Health Dictionary
n. drugs administered to a patient before an operation (usually one in which an anaesthetic is used). Premedication usually comprises injection of a sedative (such as a *benzodiazepine, to calm the patient down, together with a drug, such as *hyoscine, to dry up the secretions of the lungs (which might otherwise be inhaled during anaesthesia).
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Atropine

An anticholinergic drug derived from belladonna. Atropine is used to dilate the pupil in eye conditions

such as iritis (inflammation of the iris) and corneal ulcer. It is also used in children before eye examination. Atropine may be included in a premedication before general anaesthesia to reduce respiratory secretions and is also used as an emergency treatment for bradycardia (abnormally slow heartbeat). It is sometimes combined with an antidiarrhoeal drug to relieve abdominal cramps accompanying diarrhoea.

Adverse effects include dry mouth, blurred vision, retention of urine, and, in the elderly, confusion.

Atropine eyedrops are rarely given to adults because they cause disturbance of vision lasting 2–3 weeks and may precipitate acute glaucoma in susceptible people.... atropine

Promethazine

An antihistamine drug used to relieve itching in a variety of skin conditions, such as eczema.

It is also used as an antiemetic drug, and sometimes as a premedication.

Possible adverse effects include dry mouth, blurred vision, and drowsiness.... promethazine

Etomidate

An intravenous agent for inducing general ANAESTHESIA prior to surgery or other procedures that require patients to be unconscious. When the drug is injected intravenously, pain sometimes occurs, but this can be minimised by premedication with an opioid analgesic (see ANALGESICS).... etomidate

Anticholinergic Drugs

A group of drugs that block the effects of acetylcholine, a chemical released from nerve endings in the parasympathetic autonomic nervous system. Acetylcholine stimulates muscle contraction, increases secretions in the mouth and lungs, and slows the heartbeat.

Anticholinergic drugs are used in the treatment of irritable bowel syndrome, urinary incontinence, Parkinson’s disease, asthma, and bradycardia (abnormally slow heartbeat).

They are also used to dilate the pupil before eye examination or surgery.

Anticholinergic drugs are used as a premedication before general anaesthesia and to treat motion sickness.

They may cause dry mouth, blurred vision, urinary retention, and confusion.... anticholinergic drugs

Hyoscine

An anticholinergic drug prescribed in 2 distinct forms.

Hyoscine butylbromide is used to relieve irritable bowel syndrome.

Hyoscine hydrobromide is used to control motion sickness and to reduce nausea in Ménière’s disease.

It is also used in eye-drops to dilate the pupil before an eye examination or surgery.

An injection of hyoscine hydrobromide is often given as part of a premedication because it dries secretions in the mouth and lungs.

Possible adverse effects of both forms include dry mouth, blurred vision, drowsiness, and constipation.... hyoscine

Metoclopramide

An antiemetic drug. It is used to prevent and treat nausea and vomiting, including that associated with migraine or caused by anticancer drugs, radiotherapy, or anaesthetic drugs. Metoclopramide may be given with a premedication to reduce the risk of inhaling vomit when under an anaesthetic. Adverse effects can include dry mouth, sedation, or diarrhoea. Large doses may cause uncontrollable movements of the face, mouth, and tongue.... metoclopramide

Midazolam

A benzodiazepine drug used as premedication.

Adverse effects include confusion, drowsiness, and dizziness.

If benzodiazepines are taken for a long period, dependence may result.... midazolam

Petechiae

Red or purple, flat, pinhead spots that occur in the skin or mucousmembranes. Petechiae are caused by a localized haemorrhage from small blood vessels. They occur in purpura and, sometimes, bacterial endocarditis. pethidine A synthetic opioid analgesic drug similar to, but less powerful than, morphine. Pethidine is used as a premedication and to relieve severe pain after operations, during childbirth, or in terminal illness. As it may cause nausea and vomiting, it is usually given with an antiemetic drug.... petechiae

Sedation

The use of a drug to calm a person.

Sedation is used to reduce excessive anxiety and to control dangerously aggressive behaviour.

It may also be used as part of premedication.... sedation

Sedative Drugs

A group of drugs used to produce sedation. Sedative drugs include sleeping drugs, antianxiety drugs, antipsychotic drugs, and some antidepressant drugs. A sedative drug is often included in a premedication.... sedative drugs

Trimeprazine

Also called alimemazine. An antihistamine drug used to relieve itching in allergic conditions, and as a premedication in children. Side effects are typical of antihistamines.... trimeprazine

Alimemazine

n. an *antihistamine drug (a *phenothiazine derivative) that also possesses sedative properties. It is mainly used in the treatment of pruritus (itching) and urticaria (nettle rash), but also for premedication. Common side-effects include drowsiness, dizziness, dryness of mouth, muscular tremor and incoordination, and confusion.... alimemazine

Diazepam

n. a long-acting *benzodiazepine used for the short-term relief of acute anxiety and insomnia and in the treatment of delirium tremens, status epilepticus, and febrile convulsions; it is also used as a *premedication. Diazepam is administered by mouth, injection, or rectally and can cause dependence; side-effects include drowsiness and lethargy, confusion, and muscle weakness.... diazepam

Feticide

n. the destruction of a fetus in the uterus by injection of potassium chloride into the fetal heart to stop any pulsation and other signs of life before induced abortion and following premedication to the mother. This is usually performed to achieve a late-stage termination of pregnancy (after 21 weeks), for example because of major abnormalities in the fetus.... feticide

Lorazepam

n. a *benzodiazepine used to relieve moderate or severe anxiety and tension, including that associated with insomnia. It is also used for premedication and for treating status epilepticus. It may cause drowsiness, dizziness, blurred vision, and nausea.... lorazepam

Medication

n. 1. a substance administered by mouth, applied to the body, or introduced into the body for the purpose of treatment. See also premedication. 2. treatment of a patient using drugs.... medication

Temazepam

n. a *benzodiazepine used for the short-term treatment of insomnia and in *premedication before minor surgery. Common side-effects include drowsiness, dizziness, and loss of appetite.... temazepam



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