A digestive ENZYME – also known as a proteolytic enzyme – that breaks down PROTEIN in food as part of the digestive process. The complex protein molecules are reduced to their constituent AMINO ACIDS.
n. any enzyme that catalyses the splitting of a protein. See also proteolytic enzyme.
A new group of drugs which, in combination with antiviral agents, are used to treat AIDS (see AIDS/HIV). They inhibit the activity of PROTEASE, an enzyme produced by HIV, and which breaks down proteins. The drugs have recently been introduced: those in use are indinavir, nel?navir, ritonavir and saquinavir.... protease inhibitors
any one of a class of drugs used in the treatment of HIV infection and *AIDS. Used in combination with other *antiretroviral drugs, they act by inhibiting the action of protease, an enzyme produced by HIV that cleaves two precursor proteins into smaller fragments. These fragments are required for viral growth, infectivity, and replication. Protease inhibitors include atazanavir, indinavir, lopinavir and ritonavir (which are used in combination), saquinavir, and tipranavir. Side-effects include nausea, vomiting, diarrhoea, and rashes; these drugs are also associated with hyperglycaemia and *lipodystrophy. See also boceprevir.... protease inhibitor
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