Sen Health Dictionary

Sen: From 2 Different Sources


(Vietnamese) Resembling the lotus flower
Health Source: Medical Dictionary
Author: Health Dictionary

Senna

Cassia acutifolia. N.O. Leguminosae.

Synonym: Alexandrian Senna, Cassia, East Indian Senna, Tinnevelly Senna.

Habitat: Imported from Alexandria, East Indies, and the Near East.

Features ? Leaves, grey-green, lanceolate, unequal and varying at the base, between half an inch and one and a half inches long, and about a third of an inch across. Tinnevelly Senna leaves are broader near the middle and proportionately longer than the Alexandrian leaves. The commercial "Mecca Senna" is usually badly picked, and of poor quality generally. Pods (Alexandrian) green, about two inches by a quarter-inch ; East Indian narrower and darker coloured. Taste, sickly sweet.

Part used ? Leaves, pods.

Action: Laxative, cathartic.

For occasional and chronic constipation, dyspepsia, and disordered stomach. Two ounces of the leaves may be infused in 1 pint of boiling water and allowed to stand for an hour before use in wineglass doses. Any possibility of griping will be avoided if 1 drachm of Ginger is added to the Senna leaves before infusing.

The Alexandrian leaves and pods are considered superior to the East Indian kind as, with most people, they act more mildly, but with equal certainty.... senna

Sensitivity

A high rate of detection of “true positives”, for example, the fraction of subjects who actually received good care who are classified as recipients of good care. For medical screening tests, sensitivity is the proportion of truly diseased persons in the screened population who are identified as diseased by the screening test. Sensitivity is a measure of the probability of correctly diagnosing a case, or the probability that any given case will be identified by the test (synonymous with ‘true positive rate’).... sensitivity

Senility

The generalized characterization of progressive decline in mental or physical functioning as a condition of the ageing process. Within geriatric medicine, this term has limited meaning and has generally been replaced by more specific terminology.... senility

Senile Dementia

DEMENTIA was traditionally divided into presenile and senile types; this is increasingly recognised as an arbitrary division of a condition in which there is a general and often slow decline in mental capabilities. Around 10 per cent of people over 65 years of age and 20 per cent over 75 are affected by dementing illness, but people under 65 may also be affected. Treatable causes such as brain tumour, head injury, ENCEPHALITIS and alcoholism are commoner in younger people. Other causes such as cerebrovascular disease – which is a major factor, especially among older people – or ALZHEIMER’S DISEASE are not readily treatable, although ANTIHYPERTENSIVE DRUGS for the former disorder may help, and symptomatic treatment for both is possible.

Individuals with dementia suffer a gradual deterioration of memory and of the ability to grasp what is happening around them. They often cover up their early failings and the condition may ?rst become apparent as a result of emotional outbursts or uncharacteristic behaviour in public. Eventually personal habits and speech deteriorate and they become thoroughly confused and di?cult to look after. Treatment is primarily a matter of ameliorating the symptoms, coupled with a sympathetic handling of the sufferer and the relatives. Admission to hospital or nursing home may be necessary if relatives are unable to look after the patient at home. (See also MEDICINE OF THE AGEING.)... senile dementia

Sensation

See PAIN; TOUCH.... sensation

Sensory Cortex

See BRAIN.... sensory cortex

Sensory Deprivation

A substantial reduction in the volume of SENSORY information impinging on the body – for instance, sitting in a dark, silent room. Prolonged deprivation is potentially harmful as the body needs constant stimulation in order to function normally. The main input organs are the eyes, ears, skin and nose. The absence of sensations disorients a person and results in neurological dysfunction. Some interrogation techniques involve sensory deprivation to ‘soften up’ the individual being questioned.... sensory deprivation

Arcus Senilis

See under EYE, DISORDERS OF.... arcus senilis

Indian Senna

Cassia senna

Caesalpiniaceae

San: Svarnapatri;

Hin: Sanay, Sana Ka Patt;

Ben: Sonamukhi;

Mal: Sunnamukki, Chonnamukki, Nilavaka;

Tam: Nilavirai, Nilavakai;

Tel: Netatangedu

Importance: Indian Senna or Tinnevelly senna is a shrub very highly esteemed in India for its medicinal value. The leaves are useful in constipation, abdominal disorders, leprosy, skin diseases, leucoderma, splenomegaly, hepatopathy, jaundice, helminthiasis, dyspepsia, cough, bronchitis, typhoid fever, anaemia, tumours and vitiated conditions of pitta and vata (Warrier et al,1994). It is used in Ayurvedic preparations; “Pancha Sakara Churna”, “Shat Sakara Churna” and “Madhu Yastyadi Churna” used for constipation. Its use is widespread in Unani system and some of the important products of this system containing senna are “Itrifal Mulayyin”, “Jawarish Ood Mulayyin”, “Hab Shabyar”, “Sufuf Mulliyin”, “Sharbat Ahmad Shahi”, etc. used as a mild laxative (Thakur et al, 1989).

Distribution: The plant is of Mediterranean origin. It is found in Somalia, Saudi Arabia, parts of Pakistan and Kutch area of Gujarat. It is largely cultivated in Tirunelveli, Ramanathapuram, Madurai and Salem districts of Tamil Nadu.

Botany: The genus Cassia, belonging to the family Caesalpiniaceae, comprises of a number of species, namely,

C. senna Linn. syn. C. angustifolia Vahl.

C. absus Linn.

C. alata Linn.

C. auriculata Linn.

C. burmanni Wight. syn. C. obovata (Linn.) Collad.

C. glauca Lam.

C. javanica Linn.

C. mimosoides Linn.

C. obtusifolia Linn. syn. C. tora Linn.

C. occidentalis Linn.

C. pumila Lam.

C. slamea Lam.

C. acutifolia Delile.

C. sophera Linn.

C. senna is a shrub or undershrub, 60-75cm in height with pale subterete or obtusely angled erect or spreading branches. Leaves are paripinnate. Leaflets are 5-8 in number, ovate-lanceolate and glabrous. Flowers are yellowish, many and arranged in axillary racemes. Fruits are flat legumes, greenish brown to dark brown and nearly smooth (Chopra et al,1980, Warrier et al,1994).

In commerce, the leaves and pods obtained from C. senna are known as “ Tinnevelly Senna” and those from C. acutifolia Delile. as “Alexandrian Senna”. The leaves of C. acutifolia are narrower than C. senna, otherwise both resemble to a large extent (Thakur et al, 1989). All the true Sennas have the portions of their leaves unequally divided. In some kinds the lower part of one side is reduced to little more than a line in breadth, while the other is from a quarter to half an inch in breadth. The drug known under the name of East Indian Senna is nearly free from adulteration; and as its properties appear identical with those of the Alexandrian and the price being less, it probably will supersede it in general practice. Its size and shape readily identify it (Graves, 1996).

Agrotechnology: The plant requires a mild subtropical climate with warm winters which are free from frost for its growth. Semiarid areas with adequate irrigation facilities are ideal for cultivation. Areas having high rainfall, humidity and poor drainage are not suitable. Light or medium loamy soils with adequate drainage and pH varying from 7.0-8.2 are preferable. In South India both summer and winter crops are possible. The plant is propagated by seeds. The seed rate required is 15-20kg/ha. Seeds are sown in October-November (winter rainfed crop) or in February-March (irrigated crop). Higher seed rate is required for unirrigated crop. Seeds are sown in lines 30cm apart. Application of 5-10t of FYM/ha before planting or raising a green manure crop is beneficial. About 40kg N and 25-50kg P2O5/ha applied as basal dressing and 40kg N/ha applied in 2 split dozes as top dressing gave better yield. While the rainfed crop is grown without irrigation, the irrigated crop requires 5-8 light irrigations during the entire growing season. The crop requires 2-3 weedings and hoeings in order to keep it free from weeds. Alternaria alternata causes leaf spot and dieback but the disease is not serious. In North India, the plant is attacked by the larvae of butterfly Catopsilia pyranthe which can be controlled by planting the crop in March-April instead of June-July. Under irrigated conditions, the first crop is obtained after 90 days of planting. The leaves are stripped by hand when they are fully green, thick and bluish-green in colour. The second crop is taken 4 weeks after the first harvest and the third 4-6 weeks after the second one. The last harvest of leaves is done when the entire crop is harvested along with the pods. Yield under irrigated conditions is nearly1.4t of leaves and 150kg pods/ha and under unirrigated conditions is 500-600kg leaves and 80-100kg pods/ha. The leaves are dried in thin layers under shade so as to retain the green colour and the pods are hung for 10-12 days to get dried. The leaves and pods are cleaned, graded and marketed (Husain et al, 1993).

Properties and Activity: Leaves contain glucose, fructose, sucrose and pinnitol. Mucilage consists of galactose, arabinose, rhamnose and galacturonic acid. Leaves also contain sennoside-C(8,8’- diglucoside of rhein-aloe-emodin-dianthrone). Pods contain sennosides A and B, glycoside of anthraquinones rhein and chrysophanic acid. Seeds contain -sitosterol (Husain et al, 1992). Leaves and pods also contain 0.33% -sterol and flavonols-kaempferol, kaempferin, and iso-rhamnetin. Sennoside content of C. acutifolia is higher ranging from 2.5% to 4.5% as compared to C. angustifolia ranging from 1.5 % to 2.5%.

The purgative activity of Senna is attributed to its sennosides. The pods cause lesser griping than the leaves. Leaf and pod is laxative. The leaves are astringent, bitter, sweet, acrid, thermogenic, cathartic, depurative, liver tonic, anthelmintic, cholagogue, expectorant and febrifuge.... indian senna

Sensory

Description applied to the part of the nervous system dedicated to bringing information on sensations affecting the body to the brain. The opposite of sensory nerves is motor nerves; these carry instructions for action to the voluntary muscles in the body.... sensory

Sensitization

The initial exposure of a person to an allergen or other substance recognized as foreign by the immune system, which leads to an immune response. On subsequent exposures to the same substance, there is a much stronger and faster immune reaction. This forms the basis of allergy and other types of hypersensitivity reaction.... sensitization

Acacia Senegal

Willd.

Synonym: A. verek Guillem and Perr.

Family: Mimosaceae.

Habitat: Native to Sudan. Cultivated in dry parts of western India.

English: Gum arabic tree.

Ayurvedic: Shveta Babbuula.

Action: The tree yields the true Gum arabic of commerce. Mucilaginous, demulcent, emulsifying agent. Used as an ingredient in compounds for treatment of diarrhoea, catarrh.

Bechic, antihaemorrhagic, antiinflammatory. Stembark—antiinflammatory, spasmolytic. Root— used for dysentery and urinary discharges.

The gum consists mainly of arabin. It is the salt of an organic acid, arabic acid, with metals such as calcium, magnesium and potassium.

The stembark gives octacosanol, beta-amyrin, uvaol, beta-stosterol and its glucoside and erthrodiol. An alkaloid, dimethyltryptamine has been isolated from the leaves.... acacia senegal

Biophytum Sensitivum

(Linn.) DC.

Synonym: Oxalis sensitiva Linn.

Family: Oxalidaceae.

Habitat: Throughout tropical India.

Ayurvedic: Lajjaalu (var.) Vipareet Lajjaalu (non-classical), Alam- bushaa (Hindi commentators have equated it with Gorakh Mun- di, Sphaeranthus indicus Linn., Asteraceae.)

Folk: Lajoni, Jhalai, Lakajana.

Action: Plant—used in insomnia, convulsions, cramps, chest-complaints, inflammations, tumours, chronic skin diseases. Ash—in stomachache. Leaves— diuretic, astringent, antiseptic. Paste is applied to burns, contusions and wounds. Decoction is given in strangury, asthma and phthisis. Roots—decoction is given in lithia- sis. Mature leaves are recommended in diabetes; contain an insulin-like principle.

A saline extract of leaves showed hy- poglycaemic activity in rabbits.... biophytum sensitivum

Group Senior Assisted Housing

See “assisted living facility”.... group senior assisted housing

Khaya Senegalensis

A. Juss.

Synonym: Melia dubia Cav.

Family: Meliaceae.

Habitat: Native to South Africa. Planted in forest nurseries and plantation at Pune and Vada (Maharashtra).

English: African Mahogany.

Action: Anti-inflammatory, cardiogenic.

Methanolic extract of the stem bark showed cardiovascular (cardiogenic) effect in rodents by increasing blood pressure and vasoconstriction of the arota partly due to the stimulation of beta-receptors and alpha-adreno- ceptors.

Alcoholic extract of the stem bark showed anti-inflammatory activity... khaya senegalensis

Senecio Jacquemontianus

Benth.

Family: Compositae; Asteraceae.

Habitat: The Western Himalayas and Kashmir at elevation of 3,0003,900 m.

Folk: Poshkar, Hatermuula (Kashmir).

Action: Root—nervine tonic. Used as an adulterant of Saussurea lappa.

Whole plant extract gave senecio- nine.

Habitat: The Nilgiris and Uttar Pradesh. Introduced into Indian gardens

English: Groundsel.

Action: Formerly used as a diuretic, diaphoretic and emmenagogue, in dysmenorrhoea and bilious pains. No more recommended for internal use due to high concentration of hepatotoxic alkaloids. Infusion is used as a lotion in chronic mastitis, gout and haemorrhoids. Extracts of the plant are haemostatic.

From the dried plant material alkaloids (0.053-00.095%) have been isolated, including, seneciphylline, sene- cionine and retrorsine. Senecionine and retrorsine have been demonstrated to induce hepatic necrosis in experimental animals. The plant contains 950 mcg/kg of iodine on fresh basis.

A related species used in Western herbal, Senecio aureus Linn. (Golden Groundsel, Squaw Weed) is a uterine relaxant, stimulant to gravid uterus and a soothing drug for nervous and vascular irritability, menopausal symptoms, hot flushes. Alkaloids include senecifo- line, senescine, senecionine and otose- nine—pyrrolizidine alkaloids, in isolation, are highly toxic to liver. The plant is recommended only for external use as a douche for excessive vaginal discharge.... senecio jacquemontianus

Senga

(Greek) Form of Agnes, meaning “one who is pure; chaste” Sengah, Sengya, Sengyah, Sengia, Sengiah, Sengea, Sengeah, Sengiya, Sengiyah... senga

Senior Apartment

An age-restricted apartment where the resident is expected to live with a high degree of independence. The age of eligibility varies and is often waived for the spouse of a resident.... senior apartment

Senior Centre

A centre that provides a variety of onsite programmes (and sometimes outreach services) for older adults, including recreation, socialization, congregate meals, and some health services. Usually a good source of information about area programmes and services.... senior centre

Senior Citizen

Alternative term for an older person.... senior citizen

Sennett

(French) One who is wise Senett, Sennette, Senette, Senet, Senete, Sennetta, Senetta, Senneta, Seneta... sennett

Kinaesthetic Sensations

A term used to describe those sensations which underlie muscle tension and position of joint and muscle. These sensations send impulses along nerves to the brain, and thus inform it of the position of the limb in space and of the relative position to each other of individual muscles and muscle-groups and of joints.... kinaesthetic sensations

Sena

(Latin) One who is blessed Senna, Senah, Sennah... sena

Senalda

(Spanish) A sign; a symbol Senaldah, Senaldia, Senaldiya, Senaldea, Senaldya... senalda

Seneca

(Native American) A tribal name Senecka, Senecca, Seneka... seneca

Senona

(Spanish) A lively woman Senonah, Senonna, Senonia, Senoniya, Senonea... senona

Señora Mueller

Manufactured herbal preparation sold at botánicas and used for women’s health conditions, including menopause, infertility, vaginal infections, menstrual irregularities and uterine fibroids.... señora mueller

Senna Tea

Senna tea is made out of senna, which is an herb that contains compounds called anthraquinones, resulting in intestinal contractions. It is a purgative, similar to aloe and rhubarb and is mainly used in alleviating constipation. It can be found in Middle Eastern, African and Asian countries. Description of Senna Tea Sennas plants are mainly shrubs, its yellow flowers don’t produce nectar and its fruit is a legume. You can find sennas also as herbs or even small trees, used for ornamental purposes. Benefits of Senna Tea Little is known about the potential benefits of senna tea, but being a purgative herb it is used today as a laxative by making muscles to contract, thus stimulating bowel movements, helping in the reduction of constipation. It is sometimes used before undertaking colonoscopy-a procedure used in screening colon cancer. Besides senna tea is being used as a way of losing weight, although there are some potential risks involving the intake of senna, as we are about to find out. Side effects and risks of Senna Tea Senna tea has to be used no more than 2 weeks, because of its high risk of dysfunction of bowel, according to the national institute of Health (NIH). Other risks imply: muscle weakness, liver damage, or heart function disorders. A side effect of taking senna medication is abdominal cramps and even Malanosis coli, a brown discoloration of the colon wall. The consumption of senna tea over an extensive period of time can produce toxicity to the liver according to a 2005 report of the Annals of Pharmacotherapy. Because there is no significant medical research taken into sennas beneficial effects on the body it cannot be used in health purposes yet. Preparation of Senna Tea You can boil 100 grams of the tea leaves in distilled water with 5 grams of fresh sliced ginger. Cover it for almost 15 minutes, strain, and drink hot or cold. Careful though if you leave it long enough to steep it will become stronger and therefore it could lead to abdominal cramping. Senna tea is a strong, dangerous medicine used in modern times mostly in colon issues. You shouldn’t try to use Senna tea as a cure for more than a week and do it preferably at the doctor’s advice.... senna tea

Sensitisation

See ALLERGY; ANAPHYLAXIS.... sensitisation

Sensors

Cells or tissues that monitor the internal and external environment, either neurologically or chemically, and can initiate compensatory action or communicate to other parts that can react.... sensors

Senta

(German) Acting as an assistant Sentah, Sente... senta

Sentia

(Latin) In mythology, goddess of children’s development Sentiah, Sensia, Senzia... sentia

Sentinel Event

An unexpected occurrence or variation involving death or serious physical or psychological injury, or the risk thereof. Serious injury specifically includes loss of limb or function. The event is called “sentinel” because it signals a need for closer attention.... sentinel event

Dementia, (senile)

Progressive loss of brain cells, atrophy; caused by stress and a number of diseases: Huntingdon’s Chorea, Alzheimer’s Disease, Pick’s Disease, syphilis, trauma, and by certain sedative, anxiolytic, diuretic and hypotensive drugs.

Symptoms. Disorientation, failure of memory for recent events, failure to comprehend, unable to form elemental judgements, confusion, ataxia (lack of coordination of muscles), emotional instability with outbursts, forgetful.

Alternatives. Remedies known to sustain the brain. Nervines and alteratives believed to leach from the body deposits of toxic minerals: aluminium, sulphur, mercury, etc. Gotu Kola, Ginseng, Ginkgo, Vitamin E conserve oxygen. Pulsatilla – success reported for mental outbursts. Vasodilator of value. Ginkgo favourably reported.

Teas. Basil, Ginseng, Gotu Kola, German Chamomile, Horsetail, Yarrow.

Tea. Formula. Equal parts, Ginkgo, German Chamomile, Yarrow. 1 heaped teaspoon to each cup boiling water; infuse 5-15 minutes; 1 cup thrice daily.

Tablets/capsules. Prickly Ash, Ginseng, Ginkgo, Kelp, Pulsatilla.

Powders, Liquid Extracts, Tinctures. Combine: Gotu Kola 3; Vervain 2; Rosemary 1. Doses.

Powders: 500mg; two 00 capsules or one-third teaspoon. Liquid Extracts: 1 teaspoon. Tinctures: 2 teaspoons. In water, honey or fruit juice thrice daily.

Incontinence. A frequent problem for which American Cranesbill is indicated.

Aromatherapy. Inhalation: Feverfew, Thyme.

Contra-indicated: Black Cohosh.

Diet. Low salt. Low fat. High fibre. Egg yolk. Lecithin.

Supplements. Folic acid, Vitamins B-complex, B12, C and E. Selenium, to conserve oxygen. Magnesium, Manganese, Zinc.

General. Home help. Meals on Wheels. Service from local Psychogeriatric unit. ... dementia, (senile)

Gluten-sensitive Disease

Adult coeliac disease, coeliac sprue, non-tropical sprue, idiopathic steatorrhoea. Allergy to gluten which disturbs the small intestine by preventing the body from absorbing food nutrients. A child’s condition may worsen when put on solid cereals containing wheat, barley, rye or oats. “Allergic to pasta” disease. A change in the mucous membrane of the intestines with enzyme deficiency.

Symptoms: diarrhoea, abdominal swelling and pain, irritability, inability to gain weight, neuritis, ulcers on tongue and mouth, low blood pressure, debility, lactase-deficiency. Breast-feeding stops coeliac disease.

Alternatives. Tea. Mix, equal parts: Raspberry leaves, Agrimony, Lemon Balm. 2 teaspoons to each cup boiling water; infuse 15 minutes. 1 cup freely.

Tablets/capsules. Goldenseal, Slippery Elm. Calamus. Fenugreek seeds, Papaya. Wild Yam.

Powders, Liquid Extracts, Tinctures. Formula. Equal parts: Sarsaparilla, Wild Yam, Stone root. Dose. Powders: 500mg (two 00 capsules or one-third teaspoon). Liquid Extracts: 30-60 drops. Tinctures: 1-2 teaspoons. In water, banana mash or honey, thrice daily.

Papaya (papain) digests wheat gluten and assists recovery. Half-1g with meals.

Aloe Vera juice. Promotes improved bowel motility, increases stool specific gravity, and reduces indication of protein putrefaction, flatulence and bloating after meals. (J. Bland PhD. JAM June 1985, p.11)

Topical. Warm hip baths of Lemon Balm, Chamomile, etc. (Alfred Vogel)

Diet. Gluten-free. Rice. Unpasteurised yoghurt. Buttermilk. Sweet acidophilus milk. Raw carrot juice. Bananas mashed with a little Slippery Elm or dried milk powder, carob bean powder and Soya milk. Supplementation. Vitamins A, B-complex, B6, B12, Folic acid, C, D, E, K (Alfalfa tea). Calcium, Iron and Magnesium orotates. ... gluten-sensitive disease

Senile Purpura

A skin condition in which areas of the skin develop a purplish or reddish-brown appearance due to bleeding of small blood vessels underneath.

Senile purpura is a disease of middle to old age and is more common in women.... senile purpura

Sensate-focus Technique

A method taught to couples who are experiencing sexual difficulties caused by psychological rather than physiological factors. The aim of the technique is to make both partners more aware of pleasurable bodily sensations, and to reduce anxiety about performance. It is particularly effective in treating loss of sexual desire (see sexual desire, inhibited), or inability to achieve orgasm (see orgasm, lack of), and in helping men to overcome impotence or premature ejaculation (see ejaculation, disorders of).... sensate-focus technique

Senses

See sensation.... senses

Sensorineural Deafness

Deafness due to problems with the inner ear, nerves, or the brain’s auditory area.... sensorineural deafness

Episodic Cranial Sensory Shock

see exploding head syndrome.... episodic cranial sensory shock

Senescence

n. the process of ageing, which is often marked by a decrease in physical and mental abilities. —senescent adj.... senescence

Sense

n. one of the faculties by which the qualities of the external environment are appreciated – sight, hearing, smell, taste, or touch.... sense

Sensation, Abnormal

Dulled, unpleasant, or otherwise altered sensations in the absence of an obvious stimulus.

Numbness and pins-and-needles are common abnormal sensations. The special senses can be impaired by damage to the relevant sensory apparatus (see vision, disorders of; smell; deafness; tinnitus). Other causes of abnormal sensation include peripheral nerve damage caused by diabetes mellitus, herpes zoster infection, or pressure from a tumour, and disruption of nerve pathways in the brain or spinal cord due to spinal injury, head injury, stroke, and multiple sclerosis.

Pressure on or damage to nerves can sometimes be relieved by surgery or by treatments for the cause.

In other cases, distressing abnormal sensation can be relieved only by cutting the relevant nerve fibres or by giving injections to block the transmission of signals.... sensation, abnormal

Sense Organ

a collection of specialized cells (*receptors), connected to the nervous system, that is capable of responding to a particular stimulus from either outside or inside the body. Sense organs can detect light (the eyes), heat, pain, and touch (the skin), smell (the nose), and taste (the taste buds).... sense organ

Sensibility

n. the ability to be affected by, and respond to, changes in the surroundings (see stimulus). Sensibility is a characteristic of cells of the nervous system.... sensibility

Sensitive

adj. possessing the ability to respond to a *stimulus. The cells of the retina, for example, are sensitive to the stimulus of light and respond by sending nerve impulses to the brain. Other *receptors are sensitive to different specific stimuli, such as pressure or the presence of chemical substances.... sensitive

Sensory Nerve

a nerve that carries information inwards, from an outlying part of the body towards the central nervous system. Different sensory nerves convey information about temperature, pain, touch, taste, etc., to the brain. Compare motor nerve.... sensory nerve

Sentinel Lymph Node

the first lymph node to show evidence of metastasis (spread) of a malignant tumour (e.g. breast cancer) via the lymphatic system. Absence of cancer cells in the sentinel node indicates that more distal lymph nodes will also be free of metastasis. In breast cancer, the change in practice to perform axillary lymph node dissection only if the sentinel node contains metastatic tumour has reduced the risk of arm lymphoedema. Similarly, in head and neck squamous cell carcinomas, the sentinel lymph node procedure is used as an alternative to neck dissection.... sentinel lymph node



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