Strychnine tree Health Dictionary

Strychnine Tree: From 1 Different Sources


Strychnos nux-vomica

Loganiaceae

San: Karaskara;

Hin: Kajra, Kuchila;

Mal: Kanjiram; ;

Tam: Itti, Kagodi, Kanjirai Mar:Jharkhatchura;

Kan: Hemmushti, Ittangi;

Tel: Mushti, Mushidi; Ori: Kora, Kachila

Importance: It is a large deciduous tree, with simple leaves and white fragrant flowers.

Strychnos is highly toxic to man and animals producing stiffness of muscles and convulsions, ultimately leading to death. However, in small doses it can also serve as efficacious cure forms of paralysis and other nervous disorders. The seeds are used as a remedy in intermittent fever, dyspepsia, chronic dysentery, paralytic and neuralgic affections, worms, epilepsy, chronic rheumatism, insomnia and colic. It is also useful in impotence, neuralgia of face, heart disease, spermatorrhoea, skin diseases, toxins, wounds, emaciation, cough and cholera. Leaves are applied as poultice in the treatment of chronic wounds and ulcers and the leaf decoction is useful in paralytic complaints. Root and root bark used in fever and dysentery (Nadkarni, 1982; Kurup et al, 1979).

Distribution: The plant is distributed throughout India in deciduous forests up to 1200m. It is also found in Sri Lanka, Siam, Indochina and Malaysia.

Botany: Strychnos nux-vomica Linn. is a large tree belonging to the family Loganiaceae. Leaves are simple, opposite, orbicular to ovate, 6-11.5x6-9.5cm, coriaceous, glabrous, 5 nerved, apex obtuse, acute or apiculate, transverse nerves irregular and inconspicuous. Inflorescence is many flowered terminal cymes, 2.5-5cm across. Bracts (5mm) and bracteoles (1.5mm) small. Flowers are white or greenish white and fragrant. Calyx 5 lobed, pubescent and small (2mm). Corolla salver shaped, tube cylindrical slightly hairy near the base within and greenish white, tube much elongate than the lobes. Tube 7mm and lobes 2.5mm long. Lobes 5 and valvate. Stamens 5, filaments short, 0.1mm long. Anthers 1.5mm subexerted, linear oblong. Ovary 1.5 mm, pubescent, 2 celled, ovules one to many. Style 9mm, stigma capitate. Fruit is a berry, 5-6cm diameter, globose, indehiscent, thick shelled, orange red when ripe with fleshy pulp enclosing the seeds. Seeds 1-many, discoid, compressed, coin like, concave on one side and convex on the other, covered with fine grey silky hairs.

The leaf fall is during December (do not shed all the leaves at a time) and new foliage appears in February. Flowering is during March - April and fruiting during May - December. Fruits take about 8-9 months to mature.

Properties and activity: Strychnine and brucine are the most important and toxic alkaloids present in the plant. They occur not only in the seeds but also in roots, wood, bark, fruit pulp and hard fruit shells. The minor alkaloids present in the plant are vomicine, -colubrine, -colubrine, pseudostrychnine and N-methyl-sec-pseudobrucine (novacine). Loganin a glycoside is also present (Warnat, 1932; Martin et al, 1953; Guggisberg et al, 1966; Bisset and Chaudhary, 1974). Chatterji and Basa (1967) reported vomicine as the major constituent alkaloid along with unidentified alkaloid in leaves and identified another alkaloid kajine (N-methyl pseudostrychnine) from the leaves of very young plants.

Root bark of S. nux-vomica yeilded 4-hydroxy-3-methoxy strychnine, 4 hydroxy strychine, nor-macusine, a new alkaloid 12 , 13 dihydro-12 -hydroxy isostrychnine named protostrychnine (Baser et al, 1979) methoxy strychnine, and mavacurine (Guggisberg et al, 1966). Leaves and root bark also yeilded 11 new alkaloids. 10-hydroxy strychnine, 3-12-dihydroxystrychnine, 12-hydroxy–11- methoxy strychnine, 3-12-dihydroxy- 11-methoxy strychnine,12-hydroxy strychnine-N- oxide 12-hydroxy-11-methoxy strychnine- N-oxide-19,20–dihydro isostrychnine, 16 , 17 dihydro-17 -hydroxy isostrychnine, O- methyl-macusine B, 16-epi-o-methyl–macusine B and normelinone B (Baser and Bisset, 1982).

De and Datta (1988) isolated 5 tertiary indole alkaloids viz. strychnine, brucine, vomicine, icajine and novacine from S.nux-vomica flowers. Bisset et al (1989) isolated and identified two phenolic glycosides salidroside and cuchiloside – a compound consisting of salidroside and an attached xylose unit, from the fruit of S.nux-vomica.

Rodriguez et al (1979) isolated an indole alkaloid from the seeds of S. nux- vomica and identified as a 3-methoxy icajine. A new alkaloid 15-hydroxy strychnine has been isolated from the seeds and the structure of the alkaloid established by spectroscopic data (Galeffi et al, 1979). Cai et al (1990a) isolated 4 new alkaloids isobrucine, isobrucine N-oxide, isostrychnine N-oxide and 2 hydroxy–3-methoxy strychnine from the heat treated seeds of S. nuxvomica and the structure of the alkaloids were determined by 13 CNMR (Cai et al, 1994). Cai et al (1990 b) studied the changes in the alkaloid composition of the seeds during drug processing. Saily et al (1994) determined the mineral elements in Strychnos nux-vomica. Corsaro et al (1995) reported polysaccharides from the seeds of Strychnos species.

Seeger and Neumann (1986) reviewed the physico-chemical characteristics, occurrence, identification, utilisation, poisoning, toxicity, kinetics, differential diagnosis and therapeutic uses of strychnine and brucine. Aspergillus niger, A. flavus and Pencillium citrinum showed regular association with Strychnos seeds and effectively deteriorated the alkaloid content of the seeds (Dutta, 1988; Dutta and Roy, 1992). Nicholson (1993) described the history, structure and synthesis of strychnine which occur in the seeds of S. nux-vomica. Rawal and Michoud (1991) developed a general solution for the synthesis of 2- azabicyclo (3.3.1) nonane substructure of Strychnos alkaloids.

Villar et al (1984) and Hayakawa et al (1984) developed HPLC method for the analysis of strychnine and brucine. Graf and Wittliner (1985), Kostennikova (1986) and Gaitonde and Joshi (1986) suggested different methods for the assay of strychnine and brucine. Biala et al, (1996) developed new method for the assay of alkaloids in S. nux- vomica.

The seeds are bitter, acrid, alexeteric, aphrodisiac, appetiser, antiperiodic, anthelmintic, digestive, febrifuge, emmenagogue, purgative, spinal, respiratory and cardiac stimulant and stomachic. The bark is bitter, and tonic and febrifuge (Nadkarni, 1954; Kurup et al, 1979; Warrier et al, 1996).

The quarternery alkaloid from the root bark of the Sri Lankan plant exhibited muscle-relaxant activity (Baser and Bisset, 1982). Antimicrobial activity of indole alkaloid isolated from the Strychnos nux-vomica was studied by Verpoorte et al, 1983. Shukla et al (1985) evaluated the efficacy of Rasnadigugglu compound consisting of S. nux-vomica, on rheumatoid arthritis and found to be effective in reducing inflammatory oedoma and rheumatoid arthritis. It also exhibited analgesic activity. A compound Unani formulation containing S. nux-vomica significantly attenuated withdrawal intensity in morphine dependent rats (Zatar et al, 1991). Shahana et al (1994) studied the effect of Unani drug combination (UDC) having Strychnos nux-vomica on the abstinence syndrome in moderately and severely morphine dependent rats. The UDC strikingly suppressed the abstinence syndrome was seen to possess central depressant and analgesic action.

Melone et al (1992) reported brucine-lethality in mice. Panda and Panda (1993) and Satyanarayanan et al (1994) reported antigastric ulcer activity of nux vomica in Shay rats. Banerjee and Pal (1994) reported the medicinal plants used by the tribals of plain land in India for hair and scalp preparation and S. nux-vomica being used to cure alopecia (baldness) by the tribals. Tripathi and Chaurasia (1996) studied the effect of S. nux-vomica alcohol extract on lipid peroxidation in rat liver.
Health Source: Tropical Medicinal Plants
Author: Health Dictionary

Fringe-tree

Chionanthus virginica. N.O. Oleaceae.

Synonym: Old Man's Beard, Snowdrop Tree.

Habitat: U.S.A

Features ? A small tree with snow-white flowers which hang down like fringe—hence the common name and synonyms. Root about one-eighth inch thick, dull brown with irregular concave scars on outer surface, inside smooth, yellowish-brown. Fracture short, inner layer shows projecting bundles of stone cells. Very bitter taste.

Part used ? Root bark.

Action: Alterative, hepatic, diuretic, tonic.

In stomach and liver disorders, and poor digestive functioning generally. Also finds a place in gall-stone prescriptions and those for certain female disorders, in which latter Pulsatilla is another frequent constituent. The 1 ounce to 1 pint infusion is taken internally in 1-4 tablespoonful doses, and is applied as lotion and injection.... fringe-tree

Strychnine

An alkaloid (see ALKALOIDS) derived from Strychnos nux-vomica, the seeds of an East Indian tree, as well as from the seeds of several other closely allied trees and shrubs. It is a white crystalline body possessed of an intensely bitter taste, more bitter perhaps than that of any other substance, and it is not very soluble in water. It stimulates all parts of the nervous system, and was at one time widely used for this purpose. Strychnine poisoning is fortunately rare. It shows itself in CONVULSIONS, which come on very speedily after the person has taken the poison. The mental faculties remain unaffected, and the symptoms end in death or recovery within a few hours.

Treatment The patient should be kept quiet. Arti?cial respiration may be necessary and intravenous BENZODIAZEPINES to prevent convulsions may also be needed. (See POISONS; also APPENDIX 2: ADDRESSES: SOURCES OF INFORMATION, ADVICE, SUPPORT AND SELFHELP.)... strychnine

Carob Tree

Ceratonia siliqua

Description: This large tree has a spreading crown. Its leaves are compound and alternate. Its seedpods, also known as Saint John’s bread, are up to 45 centimeters long and are filled with round, hard seeds and a thick pulp.

Habitat and Distribution: This tree is found throughout the Mediterranean, the Middle East, and parts of North Africa.

Edible Parts: The young tender pods are edible raw or boiled. You can pulverize the seeds in mature pods and cook as porridge.... carob tree

Cuipo Tree

Cavanillesia platanifolia

Description: This is a very dominant and easily detected tree because it extends above the other trees. Its height ranges from 45 to 60 meters. It has leaves only at the top and is bare 11 months out of the year. It has rings on its bark that extend to the top to make is easily recognizable. Its bark is reddish or gray in color. Its roots are light reddish-brown or yellowish-brown.

Habitat and Distribution: The cuipo tree is located primarily in Central American tropical rain forests in mountainous areas.

Edible Parts: To get water from this tree, cut a piece of the root and clean the dirt and bark off one end, keeping the root horizontal. Put the clean end to your mouth or canteen and raise the other. The water from this tree tastes like potato water.

Other Uses: Use young saplings and the branches’ inner bark to make rope.... cuipo tree

Horseradish Tree

Moringa pterygosperma

Description: This tree grows from 4.5 to 14 meters tall. Its leaves have a fernlike appearance. Its flowers and long, pendulous fruits grow on the ends of the branches. Its fruit (pod) looks like a giant bean. Its 25-to 60-centimeter-long pods are triangular in cross section, with strong ribs. Its roots have a pungent odor.

Habitat and Distribution: This tree is found in the rain forests and semievergreen seasonal forests of the tropical regions. It is widespread in India, Southeast Asia, Africa, and Central America. Look for it in abandoned fields and gardens and at the edges of forests.

Edible Parts: The leaves are edible raw or cooked, depending on their hardness. Cut the young seedpods into short lengths and cook them like string beans or fry them. You can get oil for frying by boiling the young fruits of palms and skimming the oil off the surface of the water. You can eat the flowers as part of a salad. You can chew fresh, young seedpods to eat the pulpy and soft seeds. The roots may be ground as a substitute for seasoning similar to horseradish.... horseradish tree

Pepper Tree

Purification, Healing, Protection... pepper tree

Tree Fern

Various genera

Description: Tree ferns are tall trees with long, slender trunks that often have a very rough, barklike covering. Large, lacy leaves uncoil from the top of the trunk.

Habitat and Distribution: Tree ferns are found in wet, tropical forests.

Edible Parts: The young leaves and the soft inner portion of the trunk are edible. Boil the young leaves and eat as greens. Eat the inner portion of the trunk raw or bake it.... tree fern

Cashew Tree Fruit

Anacardium occidentale L. Active ingredient: anacardic acid – an inhibitor of prostaglandin synthetase. Kills laval mosquitoes and water snails. Dumped by natives into ponds where mosquitoes and snails breed. The apple-like fruit serves as a pesticide to control malaria, schistosomiasis and other parasitic diseases from drinking water. (Dr Isao Kubo, University of California-Berkeley, USA)

Leaves used by natives of West Africa for malaria. ... cashew tree fruit

Maidenhair Tree

See: GINKGO TREE. ... maidenhair tree

Bronchial Tree

a branching system of tubes conducting air from the trachea (windpipe) to the lungs: includes the bronchi (see bronchus) and their subdivisions and the *bronchioles.... bronchial tree

Tea Tree Essential Oil

Tea Tree Essential Oil

Tea tree oil is often referred to as “medicine cabinet in a bottle,” as it’s remedies are seemingly endless. Check out these 79 uses for the ultimate survival remedy:
  1. Abrasions and minor cuts
  2. Acne
  3. Air freshener
  4. Allergies
  5. Arthritus
  6. Asthma
  7. Athletes foot
  8. Baby care
  9. Bacterial infections
  10. Bad breath
  11. Bladder infection
  12. Blisters
  13. Boils
  14. Bronchial congestion
  15. Bronchitus
  16. Bruises
  17. Bunions
  18. Burns
  19. Calluses/corns
  20. Canker sores
  21. Carbuncies
  22. Chapped lips
  23. Chicken pox
  24. Chigger bite
  25. Cold sores
  26. Coughs
  27. Dandruff
  28. Dermatitus
  29. Dry skin
  30. Eczema
  31. Emphysema
  32. Flea bites
  33. Gout
  34. Gum disease
  35. Head lice
  36. Hives
  37. Homemade mouthwash
  38. Household cleaning
  39. Immune system
  40. Infected wounds
  41. Inflammation
  42. Ingrown hair
  43. Insect repellant
  44. Jock itch
  45. Laryngitis
  46. Laundry helper
  47. Mildew/mold remover
  48. Mosquito bites
  49. Muscle aches/pains
  50. Mumps
  51. Nail fungus
  52. Pest control
  53. Plantar warts
  54. Psoriasis
  55. Rashes
  56. Rheumatism
  57. Ringworm
  58. Rubella
  59. Scabies
  60. Sciatica
  61. Seborrhea
  62. Shingles
  63. Shock
  64. Sinusitis
  65. Sore muscles
  66. Sore throat
  67. Staph infection
  68. Stye
  69. Sunburn
  70. Tattoos
  71. Thrush
  72. Ticks
  73. Toenail fungus
  74. Toothbrush cleaner
  75. Tonsillitus
  76. Vaginal infection
  77. Viral infections
  78. Warts
  79. Wounds
 ... tea tree essential oil

Lapacho Tree

Tabebuia avellanedae. Ipe Roxo, Pau d’arco. LaPacho herb tea. Taheebo. 1,000 year-old Inca cancer-cure. Used for centuries by the Callawaya Tribe. Still used in Bolivia, Paraguay, Brazil and the Argentine. Laprachol occurs in heartwood of some trees of the genera Tecoma and Tabebuia (N.O. Bignonaiceae). Aids immune system health. Anti-tumour. Anti-microbial. Analgesic. Anodyne. Diuretic. Antidotal. Fungicidal. Anti-fever. Anti-Candida. Anti-cancer. Anti-inflammatory, analgesic, anti-haemorrhagic. Anti-leukaemic. Indian plant C.D. shows reducible activity in Walker 256 Carcinosarcoma system in rats. Exhibits significant antitumour activity with relatively little effect on body weight. Anti-cancer experiments in human patients confirm experiments made in animals bearing malignant neoplasies. Low toxicity. Adenocarcinoma (liver, breast and prostate) and epidermoid carcinoma of womb and floor of the mouth: temporary reductions of lesions and decrease of pain. (Manoel Antonio Schmidt)

Folk history: cancer remedy (anti-mitotic action), diarrhoea, boils, leprosy, chlorosis, dysentery, eneuresis, fever, pharyngitis, snakebite, syphilis, wounds. (J.A. Duke) Large doses produce nausea and anti-coagulant tendency. Strongly commended by Professor Emeritus, Walter Accorsi, University of Sao Paulo (USP) for its therapeutic value.

Oral candidiasis: good results reported.

Decoction. 15-20g bark to 500ml (1 pint) water, gently simmered 20 minutes. 1 cup thrice daily.

Tincture. 1 part to 5 parts 60 per cent alcohol; macerate 8 days; filter. Dose: 30-60 drops thrice daily. For acute cases, dose may be doubled.

Lapacho works best taken orally.

Teabags, capsules: Rio Trading Company, Brighton, England. ... lapacho tree

Strychnine Poisoning

Strychnine is a poisonous chemical found in the seeds of Strychnos species (tropical trees and shrubs). Its main use is as an ingredient in some rodent poisons; most cases of strychnine poisoning occur in children who accidentally eat such poisons.

Symptoms begin soon after ingestion and include restlessness, stiffness of the face and neck, increased sensitivity of hearing, taste, and smell, and photosensitivity, followed by alternating episodes of seizures and floppiness. Death may occur from respiratory arrest.

The victim is given intravenous injections of a tranquillizer or a barbiturate, with a muscle-relaxant drug if needed.

Breathing may be maintained by a ventilator.

With prompt treatment, recovery usually occurs in about 24 hours.... strychnine poisoning

Tea Tree

Melaleuca alternifolia

FAMILY: Myrtaceae

SYNONYMS: Narrow-leaved paperbark tea tree, ti-tree, ti-trol, melasol.

GENERAL DESCRIPTION: A small tree or shrub (smallest of the tea tree family), with needle-like leaves similar to cypress, with heads of sessile yellow or purplish flowers.

DISTRIBUTION: Native to Australia. Other varieties have been cultivated elsewhere, but M. alternifolia is not produced outside Australia, mainly in New South Wales.

OTHER SPECIES: Tea tree is a general name for members of the Melaleuca family which exists in many physiological forms including cajeput (M. cajeputi) and niaouli (M. viridiflora), and many others such as M. bracteata and M. linariifolia – see Botanical Classification section.

HERBAL/FOLK TRADITION: The name derives from its local usage as a type of herbal tea, prepared from the leaves. Our present knowledge of the properties and uses of tea tree is based on a very long history of use by the aboriginal people of Australia. It has been extensively researched recently by scientific methods with the following results: ‘1. This oil is unusual in that it is active against all three varieties of infectious organisms: bacteria, fungi and viruses. 2. It is a very powerful immuno-stimulant, so when the body is threatened by any of these organisms ti-tree increases its ability to respond.’ .

ACTIONS: Anti-infectious, anti-inflammatory, antiseptic, antiviral, bactericidal, balsamic, cicatrisant, diaphoretic, expectorant, fungicidal, immuno-stimulant, parasiticide, vulnerary.

EXTRACTION: Essential oil by steam or water distillation from the leaves and twigs.

CHARACTERISTICS: A pale yellowy-green or water-white mobile liquid with a warm, fresh, spicy-camphoraceous odour. It blends well with lavandin, lavender, clary sage, rosemary, oakmoss, pine, cananga, geranium, marjoram, and spice oils, especially clove and nutmeg.

PRINCIPAL CONSTITUENTS: Terpinene-4-ol (up to 30 per cent), cineol, pinene, terpinenes, cymene, sesquiterpenes, sesquiterpene alcohols, among others.

SAFETY DATA: Non-toxic, non-irritant, possible sensitization in some individuals.

AROMATHERAPY/HOME: USE

Skin care: Abscess, acne, athlete’s foot, blisters, burns, cold sores, dandruff, herpes, insect bites, oily skin, rashes (nappy rash), spots, verrucae, warts, wounds (infected).

Respiratory system: Asthma, bronchitis, catarrh, coughs, sinusitis, tuberculosis, whooping cough.

Genito-urinary system: Thrush, vaginitis, cystitis, pruritis.

Immune system: Colds, fever, ’flu, infectious illnesses such as chickenpox.

OTHER USES: Employed in soaps, toothpastes, deodorants, disinfectants, gargles, germicides and, increasingly, in aftershaves and spicy colognes.... tea tree




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