Diagnosis and treatment Any person with isolated, itching, dry and scaling lesions of the skin with no obvious cause – for example, no history of eczema (see DERMATITIS) – should be suspected of having a fungal infection. Such lesions are usually asymmetrical. Skin scrapings or nail clippings should be sent for laboratory analysis. If the lesions have been treated with topical steroids they may appear untypical. Ultraviolet light ?ltered through glass (Wood’s light) will show up microsporum infections, which produce a green-blue ?uorescence.
Fungal infections used to be treated quite e?ectively with benzoic-acid compound ointment; it has now been superseded by new IMIDAZOLES preparations, such as CLOTRIMAZOLE, MICONAZOLE and terbina?ne creams. The POLYENES, NYSTATIN and AMPHOTERICIN B, are e?ective against yeast infections. If the skin is macerated it can be treated with magenta (Castellani’s) paint or dusting powder to dry it out.
Refractory fungal infection can be treated systematically provided that the diagnosis of the infection has been con?rmed. Terbina?ne, imidazoles and GRISEOFULVIN can all be taken by mouth and are e?ective for yeast infections. (Griseofulvin should not be taken in pregnancy or by people with liver failure or porphyria.) (See also FUNGUS; MICROBIOLOGY.)... fungal and yeast infections
The first, CHLAMYDIA TRACHOMATIS, has a number of strains. In men, it is a major cause of nongonococcal urethritis, which may cause a discharge from the penis. In women, the infection is usually symptomless, but it can lead to salpingitis. A baby born to a woman with chlamydial infection may acquire an acute eye condition called neonatal ophthalmia. In parts of Africa and Asia, certain strains of CHLAMYDIA TRACHOMATIS cause trachoma, a serious eye disease.
A second species of chlamydiae, CHLAMYDIA PSITTACI, mainly affects birds but can occasionally spread to people who have contact with pigeons, parrots, parakeets, or poultry, causing a type of pneumonia called psittacosis.
Treatment for chlamydial infections is with antibiotic drugs.... chlamydial infections
Fungal infections are therefore more common and serious in people taking long-term antibiotic drugs (which destroy the bacterial competition) and in those whose immune systems are suppressed by immunosuppressant drugs, corticosteroid drugs, or by a disorder such as AIDS. Such serious fungal infections are described as opportunistic infections. Some fungal infections are more common in people with diabetes mellitus.
Fungal infections can be classified into superficial (affecting skin, hair, nails, inside of the mouth, and genital organs); subcutaneous (beneath the skin); and deep (affecting internal organs).
The main superficial infections are tinea (including ringworm and athlete’s foot) and candidiasis (thrush), both of which are common. Subcutaneous infections, which are rare, include sporotrichosis and mycetoma. Deep infections are uncommon but can be serious and include aspergillosis, histoplasmosis, cryptococcosis, and blastomycosis. The fungal spores enter the body by inhalation.
Treatment of fungal infections is with antifungal drugs, either used topically on the infected area or given by mouth for generalized infections.... fungal infections
A nosocomial infection is one acquired by a patient in hospital.... nosocomial
Practising safer sex can help prevent STIs.... sexually transmitted infections
Different types of staphylococci are responsible for a variety of disorders, including skin infections such as pustules, boils, and abscesses, and a rash in newborn babies (see necrolysis, toxic epidermal); pneumonia; toxic shock syndrome in menstruating women; urinary tract infection; food poisoning; and, if the bacteria enter the circulation, septic shock, infectious arthritis, osteomyelitis, or bacterial endocarditis.... staphylococcal infections
A particular type, haemolytic streptococci, can cause tonsillitis, strep throat, scarlet fever, otitis media, pneumonia, erysipelas, and wound infections.
Another type is often responsible for urinary tract infection, and another can cause bacterial endocarditis if it enters the bloodstream.... streptococcal infections